In flies reared under 12:12 light dark zeitgeber cycle, expression of trsn^GD1918 under either the control of Scer\GAL4^nSyb.PS or the combined control of Scer\GAL4^{elav.Switch.PO} and RU486 treatment from day 3 post eclosion onwards (to restrict expression to adulthood) results in increased average sleep time under starvation but not under normal diet, associated with a significantly decreased starvation-induced sleep deprivation; the expression under the control of Scer\GAL4^nSyb.PS also decreases the waking activity under starvation but not under normal diet, and suppresses the starvation-induced increase in waking activity observed in wild-type controls.

Expression of trsn^GD1918 under the control of Scer\GAL4^Lk.PK, but not under the control of Scer\GAL4^yolk or Scer\GAL4^how-24B, leads to significantly decreased starvation-induced sleep deprivation, as compared to wild-type controls.

Adults expressing trsn^GD1918 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Expression of trsn^GD1918 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD1918} insertion line used.