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General Information
Symbol
Dmel\wtsGD1563
Species
D. melanogaster
Name
FlyBase ID
FBal0210898
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-wts-RNAi, UAS-RNAi-wts
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Pupal eye clones of cells expressing wtsGD1563 driven by Scer\GAL4αTub84B.PL exhibit increased clonal area as well as overproliferation of interommatidial cells.
Expression of wtsGD1563 under the control of Scer\GAL4hh.PU results in overgrowth of the posterior wing compartment. Expression of wtsGD1563 under the simultaneous control of both Scer\GAL4GMR.PFa and Scer\GAL4ey.200.Exel results in adults with increased eye size compared to controls. The retinas contain an excess of interommatidial cells.
Adults expressing wtsGD1563 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4pnr-MD237 results in a colour difference between the central Scer\GAL4pnr-MD237 expression domain of the notum and the surrounding lateral region in 0% or 40-50% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used. Expression under the control of Scer\GAL4pnr-MD237 may result in mild thorax closure defects, depending on the insertion line used. Expression under the control of Scer\GAL4pnr-MD237 may result in an enlarged notum, depending on the insertion line used.
External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhanced by
NOT suppressed by
Additional Comments
Genetic Interactions
Statement
Reference
Homozygous mutant clones of Df(1)djubI also expressing wtsGD1563 driven by Scer\GAL4αTub84B.PL display phenotypes that resemble clones expressing wtsGD1563 alone.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (14)