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General Information
Symbol
Dmel\ballE60
Species
D. melanogaster
Name
FlyBase ID
FBal0212320
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
nhk-1E60
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of P{EP}ballEP863 leaves part of the P{EP} element in the ball gene.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

ballE107/Df(3R)ro80b third instar larvae display chromosome condensation defects in the mitotic cells in the central nervous system, the frequency of mitotic cells (phospho-histone H3-positive) is significantly increased compared to wild-type..

Brain-squashes of ballE60 mutants reveal a higher mitotic index and frequent overcondensation of chromosomes. The frequency of anaphase is also decreased. Some anaphase cells exhibit lagging chromosomes. Except for overcondensation, which is associated with mitotic arrest, the morphology of mitotic chromosomes is generally unaffected.

In ballE60 mutants, about one third of the spindles exhibit defects in bipolarity. The defects include monopolar spindles, multipolar spindles, and formation of ectopic microtubule foci that lack Cp190.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)