Allele Disc\T:Disc\RFP^mCherry

General Information
Symbol	Disc\T:Disc\RFP^mCherry	Species	D. sp.
Name		FlyBase ID	FBal0212440
Feature type	allele	Associated gene	Disc\T:Disc\RFP

Allele class
Mutagen	in vitro construct - amino acid replacement
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - amino acid replacement (Goshima et al., 2007, FlyBase Curators, 1992-)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Contains a mutated form of the Disc\RFP coding sequence. (Goshima et al., 2007) Monomeric form of T:Disc\RFP. Contains a number of amino acid mutations relative to DsRed (see PMID:15558047 and GenBank accession AY678264). (FlyBase Curators, 1992-)
Tags	Ack^{Scer\UAS.T:Disc\RFP-mCherry} (Schoenherr et al., 2012) ana2^{MtnA.T:Disc\RFP-mCherry} (Goshima et al., 2007) Apc^{Scer\UAS.T:Disc\RFP-mCherry} (Mattie et al., 2010) asun^{βTub85D.T:Disc\RFP-mCherry} (Anderson et al., 2009) Atg8a^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Nezis et al., 2009) Atg8a^{Scer\UAS.T:Avic\GFP-EGFP,T:Disc\RFP-mCherry} (Nezis et al., 2010) Atg8a^{Scer\UAS.T:Disc\RFP-mCherry} (Chang and Neufeld, 2009) Atox1^{Scer\UAS.T:Disc\RFP-mCherry} (Hua et al., 2011) baz^{Scer\UAS.T:Disc\RFP-mCherry} (McGill et al., 2009) baz^{Ubi-p63E.T:Disc\RFP-mCherry} (Bosveld et al., 2012) blow^{Scer\UAS.T:Disc\RFP-mCherry} (Jin et al., 2011) brp^{S.Scer\UAS.T:Disc\RFP-mCherry} (Christiansen et al., 2011) Cap-H2^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Hartl et al., 2008) capt^{Scer\UAS.T:Disc\RFP-mCherry} (Medina et al., 2008) CCKLR-17D1^{Scer\UAS.T:Disc\RFP-mCherry} (Chen and Ganetzky, 2012) CG4764^{αTub84B.T:Disc\RFP-mCherry} (Burgess et al., 2012) Chc^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Li et al., 2010) Crei\ChR2^{H134R.Scer\UAS.T:Disc\RFP-mCherry} (Pulver et al., 2009) Crei\ChR2^{Scer\UAS.cHa.T:Disc\RFP-mCherry} (Hwang et al., 2007) dl^{T:Disc\RFP-mCherry} (Lund et al., 2010) Dpt^{Scer\UAS.T:Disc\RFP-mCherry} (Charroux and Royet, 2009) Ehbp1^{Scer\UAS.T:Disc\RFP-mCherry} (Giagtzoglou et al., 2012) esn^{Scer\UAS.FL.T:Disc\RFP-mCherry} (Matsubara et al., 2011) esn^{ΔLIM.Scer\UAS.T:Disc\RFP-mCherry} (Matsubara et al., 2011) Evi5^{R160A.Scer\UAS.T:Disc\RFP-mCherry} (Laflamme et al., 2012) Evi5^{Scer\UAS.T:Disc\RFP-mCherry} (Laflamme et al., 2012) g^{αTub84B.T:Disc\RFP-mCherry} (Burgess et al., 2011) gfA^{Scer\UAS.T:Disc\RFP-mCherry} (Christiansen et al., 2011) HipHop^{ms(3)K81.T:Disc\RFP-mCherry} (Gao et al., 2011) HipHop^{T:Disc\RFP-mCherry} (Gao et al., 2011) Hsap\CD4^{20x.Scer\UAS.4X.T:Disc\RFP-mCherry,T:Ivir\HA1} (Petersen and Stowers, 2011) Hsap\CLIP1^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Stramer et al., 2010) Hsap\PLCD1^{PH.4C.Scer\UAS.T:Disc\RFP-mCherry} (Khuong et al., 2010) Hsap\RAC1^{C450M.PA.Q61L.Scer\UAS.T:Disc\RFP-mCherry,T:Zzzz\PT1} (Wang et al., 2010) Hsap\RAC1^{PA.Q61L.Scer\UAS.T:Disc\RFP-mCherry,T:Zzzz\PT1} (Wang et al., 2010) Hsap\RAC1^{PA.T17N.Scer\UAS.T:Disc\RFP-mCherry,T:Zzzz\PT1} (Wang et al., 2010) Hsap\TUBA1B^{Scer\UAS.T:Disc\RFP-mCherry} (Rusan and Peifer, 2007) Hsap\UTRN^{CH.αTub84B.T:Disc\RFP-mCherry} (Goldbach et al., 2010) Ir8a^{Scer\UAS.T:Hsap\CALR,T:Disc\RFP-mCherry} (Abuin et al., 2011) jub^{Scer\UAS.T:Disc\RFP-mCherry} (Das Thakur et al., 2010) Jupiter^{Scer\UAS.T:Disc\RFP-mCherry} (McDonald et al., 2008, Chabu and Doe, 2008) kel^{KREP.Scer\UAS.P\T.T:Zzzz\SBP,T:Disc\RFP-mCherry} (Hudson and Cooley, 2010) kel^{Scer\UAS.P\T.T:Zzzz\SBP,T:Disc\RFP-mCherry} (Hudson and Cooley, 2010) kst^{Minikarst.Scer\UAS.T:Disc\RFP-mCherry} (Tjota et al., 2011) l(2)gl^{Scer\UAS.T:Disc\RFP-mCherry} (Wirtz-Peitz et al., 2008) Lam^FB2.0 (Hadjieconomou et al., 2011) Lis-1^{βTub85D.T:Disc\RFP-mCherry} (Sitaram et al., 2012) Lsd-1::Lsd-2^{2.1C.Scer\UAS.T:Disc\RFP-mCherry} (Bi et al., 2012) Lsd-1^{Scer\UAS.T:Disc\RFP-mCherry} (Tian et al., 2011) Lsd-2^{Scer\UAS.T:Disc\RFP-mCherry} (Bi et al., 2012) Mad1^{C.T:Disc\RFP-mCherry} (Emre et al., 2011) Mad1^{N.T:Disc\RFP-mCherry} (Emre et al., 2011) mira^{Scer\UAS.T:Disc\RFP-mCherry} (Cabernard and Doe, 2009) Mis12^{T:Disc\RFP-mCherry} (Goshima et al., 2007) Mmus\Cd8a^FB1.0 (Hadjieconomou et al., 2011) Mmus\Cd8a^FB1.1 (Hadjieconomou et al., 2011) Mmus\Cd8a^FB2.0 (Hadjieconomou et al., 2011) Mmus\Cd8a^{Scer\UAS.Scer\FRT.Scer\FRT-m.71.T:Avic\GFP-EGFP,T:Mmus\pm,T:Avic\GFP-mCitrine,T:Disc\RFP-mCherry,T:Avic\GFP-ECFP.Cer,T:SV5\V5} (Hadjieconomou et al., 2011) Mmus\Cd8a^{Scer\UAS.Scer\FRT.Scer\FRT-m.71.T:Disc\RFP-mCherry,T:Avic\GFP-ECFP.Cer,T:SV5\V5} (Hadjieconomou et al., 2011) Mmus\Cd8a^{Scer\UAS.T:Disc\RFP-mCherry} (Schnorrer, 2009.5.11) Mmus\Cd8a^{Scer\UAS.x.Scer\FRT-m.71.T:Disc\RFP-mCherry,T:Avic\GFP-ECFP.Cer,T:SV5\V5} (Hadjieconomou et al., 2011) Mmus\Icam5^{Scer\UAS.T:Disc\RFP-mCherry} (Nicolaï et al., 2010) Mmus\Icam5^{ΔICAM5.Scer\UAS.T:Disc\RFP-mCherry} (Nicolaï et al., 2010) Mob4^{Scer\UAS.C.T:Disc\RFP-mCherry} (Schulte, 2011.9.16) Mob4^{Scer\UAS.N.T:Disc\RFP-mCherry} (Schulte, 2011.9.16) Moe^{act.Scer\UAS.P\T.T:Disc\RFP-mCherry} (Vilmos et al., 2009) Moe^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Millard and Martin, 2008) Moe^{sqh.T:Disc\RFP-mCherry} (Parkhurst, 2011.4.14) mtm^{Scer\UAS.T:Disc\RFP-mCherry} (Velichkova et al., 2010) MtnD^{T:Disc\RFP-mCherry} (Atanesyan et al., 2011) MtnE^{T:Disc\RFP-mCherry} (Atanesyan et al., 2011) N^{Scer\UAS.T:Disc\RFP-mCherry} (Kawahashi and Hayashi, 2010) n-syb^{Ncra\QUAS.4X.T:Disc\RFP-mCherry,T:Ivir\HA1} (Petersen and Stowers, 2011) n-syb^{Ncra\QUAS.T:Disc\RFP-mCherry,T:Ivir\HA1} (Petersen and Stowers, 2011) par-6^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Doerflinger et al., 2010) Pex2^{Scer\UAS.T:Disc\RFP-mCherry} (Chen et al., 2010) Pi3K68D^{Scer\UAS.T:Disc\RFP-mCherry} (Velichkova et al., 2010) Pi4KIIα^{ACT.αTub84B.T:Disc\RFP-mCherry} (Burgess et al., 2012) Pi4KIIα^{CAT.αTub84B.T:Disc\RFP-mCherry} (Burgess et al., 2012) Pi4KIIα^{αTub84B.T:Disc\RFP-mCherry} (Burgess et al., 2012) PI31^{T:Disc\RFP-mCherry} (Bader et al., 2011) Pmi^{Scer\UAS.T:Disc\RFP-mCherry} (Rival et al., 2011) Rab3^{Ncra\QUAS.T:Disc\RFP-mCherry} (Petersen and Stowers, 2011) Rab5^{T:Disc\RFP-mCherry} (Lund et al., 2010) RanGAP^{Scer\UAS.T:Zzzz\FLAG,T:Zzzz\BLRP,T:Disc\RFP-mCherry} (Steiner et al., 2012) RanGAP^{twi.T:Zzzz\FLAG,T:Zzzz\BLRP,T:Disc\RFP-mCherry} (Steiner et al., 2012) Rbf^{N.Scer\UAS.P\T.T:Disc\RFP-mCherry,T:SV5\V5} (Ahlander et al., 2008) Rnor\CD2^{Scer\UAS.T:Disc\RFP-mCherry} (Yuan et al., 2011) Sbf^{Scer\UAS.T:Disc\RFP-mCherry} (Jean et al., 2012) sec31^{Scer\UAS.T:Disc\RFP-mCherry} (Forster et al., 2010) sel^{T:Disc\RFP-mCherry} (Stein et al., 2010) shg^{KI.T:Disc\RFP-mCherry} (Huang et al., 2009) sn^{S289A.Scer\UAS.P\T.T:Disc\RFP-mCherry} (Zanet et al., 2012) sn^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Zanet et al., 2012) SNF1A^{Scer\UAS.T:Disc\RFP-mCherry} (Mirouse et al., 2007) SNF1A^{ΔC.Scer\UAS.T:Disc\RFP-mCherry} (Kazgan et al., 2010) spdo^{L2.Scer\UAS.T:Disc\RFP-mCherry} (Couturier et al., 2012) spdo^{Scer\UAS.T:Disc\RFP-mCherry} (Benhra et al., 2011) spdo^{Δ18.Scer\UAS.T:Disc\RFP-mCherry} (Benhra et al., 2011) spn-F^{Scer\UAS.P\T.T:Disc\RFP-mCherry} (Dubin-Bar et al., 2008) sqh^{T:Disc\RFP-mCherry} (Martin et al., 2009) TrpA1^{Scer\FRT.stop.Scer\UAS.T:Disc\RFP-mCherry} (von Philipsborn et al., 2011) TrpA1^{Scer\UAS.T:Disc\RFP-mCherry} (von Philipsborn et al., 2011) Uuuu\SAS-6^{T:Disc\RFP-mCherry} (Rusan and Peifer, 2007) vas^{T:Disc\RFP-mCherry,T:Ivir\HA1} (Lerit and Gavis, 2011) VhaM8.9^{Scer\UAS.T:Disc\RFP-mCherry} (Hermle et al., 2010) Vrp1^{Scer\UAS.T:Disc\RFP-mCherry} (Jin et al., 2011) Zyx^{Scer\UAS.T:Disc\RFP-mCherry} (Warner, 2010.9.15) αTub84B^{Act5C.T:Disc\RFP-mCherry} (Goshima et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Encodes a mutant form of Disc\RFP with improved brightness and photostability. (Goshima et al., 2007)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	mCherry (Goshima et al., 2007) T:Disc\RFP^mCherry
Name Synonym
Secondary FlyBase IDs

References ( 80 )

Generate a list of	All references relating to this allele ( 80 )

List References by type	Research paper ( 66 ) Supplementary material ( 9 ) Personal communication to FlyBase ( 4 ) FlyBase analysis ( 1 )
Recent research papers ( 29 )
	Bi et al., 2012, J. Cell Sci. 125(15): 3568--3577 Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization. [FBrf0219622] Burgess et al., 2012, Development 139(16): 3040--3050 Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila. [FBrf0219013] Chen and Ganetzky, 2012, J. Cell Biol. 196(4): 529--543 A neuropeptide signaling pathway regulates synaptic growth in Drosophila. [FBrf0217500] Couturier et al., 2012, Nat. Cell Biol. 14(2): 131--139 Endocytosis by Numb breaks Notch symmetry at cytokinesis. [FBrf0217937] Giagtzoglou et al., 2012, J. Cell Biol. 196(1): 65--83 dEHBP1 Controls Exocytosis and Recycling of Delta During Asymmetric Divisions. [FBrf0217836] Jean et al., 2012, Mol. Biol. Cell 23(14): 2723--2740 Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. [FBrf0218866] Laflamme et al., 2012, J. Cell Biol. 198(1): 57--67 Evi5 promotes collective cell migration through its Rab-GAP activity. [FBrf0218839] Schoenherr et al., 2012, PLoS Genet. 8(5): e1002725 Drosophila activated cdc42 kinase has an anti-apoptotic function. [FBrf0218372] Sitaram et al., 2012, Development 139(16): 2945--2954 Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis. [FBrf0219060] Steiner et al., 2012, Genome Res. 22(4): 766--777 Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling. [FBrf0217906] Zanet et al., 2012, J. Cell Biol. 197(4): 477--486 Fascin promotes filopodia formation independent of its role in actin bundling. [FBrf0218285] Abuin et al., 2011, Neuron 69(1): 44--60 Functional architecture of olfactory ionotropic glutamate receptors. [FBrf0212725] Atanesyan et al., 2011, J. Biol. Inorg. Chem. 16(7): 1047--1056 Characterization of MtnE, the fifth metallothionein member in Drosophila. [FBrf0215591] Bader et al., 2011, Cell 145(3): 371--382 A conserved f box regulatory complex controls proteasome activity in Drosophila. [FBrf0213568] Benhra et al., 2011, Curr. Biol. 21(1): 87--95 AP-1 Controls the Trafficking of Notch and Sanpodo toward E-Cadherin Junctions in Sensory Organ Precursors. [FBrf0212697] Burgess et al., 2011, Mol. Biol. Cell 22(12): 2094--2105 AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila. [FBrf0213890] Christiansen et al., 2011, J. Neurosci. 31(26): 9696--9707 Presynapses in Kenyon Cell Dendrites in the Mushroom Body Calyx of Drosophila. [FBrf0214059] Emre et al., 2011, J. Cell Sci. 124(10): 1664--1671 A mitotic role for Mad1 beyond the spindle checkpoint. [FBrf0213557] Gao et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(12): 4932--4937 Paternal imprint essential for the inheritance of telomere identity in Drosophila. [FBrf0213318] Hadjieconomou et al., 2011, Nat. Methods 8(3): 260--266 Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. [FBrf0213120] Hua et al., 2011, Biometals 24(3): 445--453 Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila. [FBrf0213623] Jin et al., 2011, Dev. Cell 20(5): 623--638 Competition between Blown Fuse and WASP for WIP Binding Regulates the Dynamics of WASP-Dependent Actin Polymerization In Vivo. [FBrf0213682] Lerit and Gavis, 2011, Curr. Biol. 21(6): 439--448 Transport of germ plasm on astral microtubules directs germ cell development in Drosophila. [FBrf0213255] Matsubara et al., 2011, Genes Dev. 25(18): 1982--1996 The seven-pass transmembrane cadherin Flamingo controls dendritic self-avoidance via its binding to a LIM domain protein, Espinas, in Drosophila sensory neurons. [FBrf0215818] Petersen and Stowers, 2011, PLoS ONE 6(9): e24531 A Gateway MultiSite Recombination Cloning Toolkit. [FBrf0215584] Tian et al., 2011, PLoS Genet. 7(4): e1001364 Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. [FBrf0213596] Tjota et al., 2011, J. Cell Sci. 124(17): 2914--2926 Annexin B9 binds to {beta}H-spectrin and is required for multivesicular body function in Drosophila. [FBrf0215049] von Philipsborn et al., 2011, Neuron 69(3): 509--522 Neuronal control of Drosophila courtship song. [FBrf0212984] Yuan et al., 2011, Science 333(6048): 1458--1462 Light-induced structural and functional plasticity in Drosophila larval visual system. [FBrf0215276] Show all research papers ...

Allele Disc\T:Disc\RFPmCherry

Allele Disc\T:Disc\RFP^mCherry