Allele Dmel\Ubx^LDN

General Information
Symbol	Dmel\Ubx^LDN	Species	D. melanogaster
Name		FlyBase ID	FBal0212728
Feature type	allele	Associated gene	Dmel\Ubx

Allele class
Mutagen	Delta2-3
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	Delta2-3 (de Navas et al., 2006)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GawB}Ubx^LDN (de Navas et al., 2006, de Navas et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class
	lethal (de Navas et al., 2006) visible (with Ubx^pbx-1), with Ubx^abx-1, Ubx^bx-3 (de Navas et al., 2011, de Navas et al., 2011, de Navas et al., 2011) visible \| homeotic, with Ubx^abx-1, Ubx^bx-3/Ubx^pbx-1 (de Navas et al., 2006) visible \| homeotic, with Ubx^abx-1, Ubx^pbx-1/Ubx^bx-3 (de Navas et al., 2006) visible \| homeotic, with Ubx^bx-3, Ubx^abx-1/Ubx^pbx-1 (de Navas et al., 2006) visible \| homeotic (with Ubx^pbx-1), with Ubx^abx-1, Ubx^bx-3 (de Navas et al., 2006, de Navas et al., 2006, de Navas et al., 2006)
Phenotype Manifest In
	capitellum (with Ubx^pbx-1), with Ubx^abx-1, Ubx^bx-3 (de Navas et al., 2011, de Navas et al., 2011, de Navas et al., 2011) haltere, with Ubx^abx-1, Ubx^bx-3/Ubx^pbx-1 (de Navas et al., 2006) haltere, with Ubx^abx-1, Ubx^pbx-1/Ubx^bx-3 (de Navas et al., 2006) haltere, with Ubx^bx-3, Ubx^abx-1/Ubx^pbx-1 (de Navas et al., 2006) haltere (with Ubx^pbx-1), with Ubx^abx-1, Ubx^bx-3 (de Navas et al., 2006, de Navas et al., 2006, de Navas et al., 2006) wing \| ectopic (with Ubx^pbx-1), with Ubx^abx-1, Ubx^bx-3 (de Navas et al., 2011, de Navas et al., 2011, de Navas et al., 2011)
Detailed Description
	Statement Reference Ubx[LDN]/Ubx[abx-1] Ubx[bx-3] Ubx[pbx-1] adults show transformation of the distal part of the haltere (the capitellum) into the wing; the haltere is bigger than normal and has bristles on the margins and veins on the surface. (de Navas et al., 2011) The haltere is partially transformed to a wing in Ubx^abx-1 Ubx^bx-3 Ubx^pbx-1/Ubx^LDN flies. (de Navas et al., 2006)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Ubx^abx-1, Ubx^bx-3, Ubx^pbx-1/Ubx^LDN has visible \| homeotic phenotype, suppressible by abd-A^{1dB5.Scer\UAS}/Scer\GAL4^Ubx-LDN (de Navas et al., 2006, de Navas et al., 2006, de Navas et al., 2006)
Phenotype Manifest In
Suppressed by
Statement Reference Ubx^abx-1, Ubx^bx-3, Ubx^pbx-1/Ubx^LDN has haltere phenotype, suppressible by abd-A^{1dB5.Scer\UAS}/Scer\GAL4^Ubx-LDN (de Navas et al., 2006, de Navas et al., 2006, de Navas et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference Expression of abd-A^{1dB5.Scer\UAS} results in an almost complete rescue of the transformed haltere phenotype of Ubx^abx-1 Ubx^bx-3 Ubx^pbx-1/Ubx^LDN flies. The P{GawB}Ubx^LDN insertion within the Ubx^LDN flies drives expresssion of abd-A^{1dB5.Scer\UAS}. (de Navas et al., 2006)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments	The partial transformation of haltere into wing which is seen in Ubx[LDN]/Ubx[abx-1] Ubx[bx-3] Ubx[pbx-1] flies is strongly suppressed by expression of either Ubx[Scer\UAS.cCa] or Ubx[IIa.Scer\UAS.cRa] under the control of Scer\GAL4[Ubx-LDN]. The partial transformation of haltere into wing which is seen in Ubx[LDN]/Ubx[abx-1] Ubx[bx-3] Ubx[pbx-1] flies is partially suppressed by expression of one copy of Ubx[IVa.Scer\UAS.cRa] under the control of Scer\GAL4[Ubx-LDN] and is almost completely suppressed by expression of two copies of Ubx[IVa.Scer\UAS.cRa] under the control of Scer\GAL4[Ubx-LDN]. (de Navas et al., 2011)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Ubx^LDN
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	de Navas et al., 2011, Development 138(1): 107--116 Integration of RNA processing and expression level control modulates the function of the Drosophila Hox gene Ultrabithorax during adult development. [FBrf0212483] de Navas et al., 2006, Mech. Dev. 123(11): 860--867 A simple and efficient method to identify replacements of P-lacZ by P-Gal4 lines allows obtaining Gal4 insertions in the bithorax complex of Drosophila. [FBrf0194816]

Allele Dmel\UbxLDN

Allele Dmel\Ubx^LDN