An Ubi-p63E promoter drives expression of a truncated form of β-Spec that lacks the PH domain. The construct is tagged with Tag:MYC.
decreased body size, with β-Specem21
decreased body size (with β-Specem21)
sterile, with β-Specem21
sterile (with β-Specem21)
Expression of β-SpecΔPH.Ubi-p63E.T:Hsap\MYC in a β-Specem21 background rescues flies rarely. These rescued flies are strikingly small in size and are sterile.
β-SpecΔPH.Ubi-p63E.Tag:MYC partially rescues β-Specem6
β-SpecΔPH.Ubi-p63E.Tag:MYC fails to rescue β-Specem21
Expression of β-SpecΔPH.Ubi-p63E.T:Hsap\MYC rescues the midline axon guidance defects of β-Specem6/Y embryos.
Expression of β-SpecΔPH.Ubi-p63E.T:Hsap\MYC generally fails to rescue β-Specem21 flies, although rare rescue flies are observed.