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General Information
Symbol
Dmel\CDaseslab-2
Species
D. melanogaster
Name
FlyBase ID
FBal0213207
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
slab2
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Mobilization of the P{lacW} element, resulting in an intragenic deletion of 855 bases that removes parts of exons 4 and 5 of the CDase gene. The original P{lacW}l(3)j8B9j8B9 insertion site is retained and there is a second insertion within CDase.

Insertion components
P{lacW}CDaseslab-2
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

CDaseslab-2 embryos appear anatomically and morphologically normal. Although mutants move spontaneously and in response before hatching, movements are less vigorous than in controls. A minority briefly generate peristaltic body contractions sufficient to emerge partly or completely from the egg case. Physiological assays show that hypertonic saline-evoked synaptic vesicle fusion is significantly impaired in CDaseslab-1/CDaseslab-2 embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Enhancer of
Statement
Reference

CDase[+]/CDaseslab-2 is an enhancer of adult brain | progressive phenotype of spinDelta58/spin10403

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)