Amino acid replacement: S20N.
UASt regulatory sequences drive expression of a predicted dominant negative form of Rab2 that is tagged at the N-terminal end with YFP.
immune response defective | adult stage, with Scer\GAL4Hml.Δ
hemocyte | adult stage, with Scer\GAL4Hml.Δ
phagocytic vesicle, with Scer\GAL4Hml.Δ
Adult hemocytes expressing Rab2S20N.Scer\UAS.T:Avic\GFP-YFP under the control of Scer\GAL4Hml.Δ show slower maturation of phagosomes containing pHrodo-conjugated S. aureus compared to wild-type controls.
Expression via Scer\GAL4pnr-MD237 results in flies with a wild type notum.