FB2025_02 , released April 17, 2025
Allele: Dmel\Rab4UASp.YFP
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General Information
Symbol
Dmel\Rab4UASp.YFP
Species
D. melanogaster
Name
FlyBase ID
FBal0215389
Feature type
allele
Associated gene
Dmel\Rab4
Associated Insertion(s)
Carried in Construct
P{UASp-YFP.Rab4}
Also Known As
UAS-YFP-Rab4, Rab4 WT, YFP-Rab4, Rab4-WT, UAS-RAB4-YFP, UAS-YFP:Rab4
Key Links
Transgenic product class
wild_type
(Zhang et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zhang et al., 2007)
Mutagen
in vitro construct
(Zhang et al., 2007)
Progenitor genotype
Carried in construct
P{UASp-YFP.Rab4}
Cytology
Description

UASp regulatory sequences drive expression of wild-type Rab4 that is tagged at the N-terminal end with YFP.

(Zhang et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Rab4
Tagged with
YFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Alzheimer's disease 1
      modeled by Hsap\APP2xAPP.SP.UAS
      (Yu et al., 2020)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Rab4Scer\UAS.P\T.T:Avic\GFP-YFP under the control of Scer\GAL4slbo.2.6 has no effect on border cell cluster integrity in the developing egg chamber.

      (Chen et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Rab4UASp.YFP, Scer\GAL4elav.Switch.PO is an enhancer of short lived | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO

      (Yu et al., 2020)
      NOT Enhancer of
      NOT Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Rab4Scer\UAS.P\T.T:Avic\GFP-YFP does not suppress the blistered wing phenotype seen when mopScer\UAS.cCa is expressed under the control of Scer\GAL4en.PU.

      (Chen et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rab4Scer\UAS.P\T.T:Avic\GFP-YFP
      Rab4UASp.YFP
      Name Synonyms
      Secondary FlyBase IDs
        References (24)