Animals expressing Rab11S25N.Scer\UAS.P\T.T:Avic\GFP-YFP
under the control of Scer\GAL4grh.D4
are lethal, show defects in larval dorsal trunk elongation (resulting in internalization of posterior spiracles into the body cavity) and the larvae are smaller than age-matched controls.
Flies expressing Rab11S25N.Scer\UAS.P\T.T:Avic\GFP-YFP
under the control of Scer\GAL4ninaE.PT
which are raised at 18[o]C prior to eclosion and then raised under 12 hour light/12 hour dark conditions show a reduction in the amplitude of the electroretinogram at 3 weeks of age. Defects in rhabdomere morphology are also seen at this age. These retinal degeneration defects are not seen if the flies are raised in constant darkness after eclosion.