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General Information
Symbol
Dmel\Rab14S49N.UASp.YFP
Species
D. melanogaster
Name
FlyBase ID
FBal0215414
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: S49N.

UASp regulatory sequences drive expression of a predicted dominant negative form of Rab14 that is tagged at the N-terminal end with YFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adult hemocytes expressing Rab14S49N.Scer\UAS.P\T.T:Avic\GFP-YFP under the control of Scer\GAL4Hml.Δ show slower maturation of phagosomes containing pHrodo-conjugated S. aureus compared to wild-type controls.

Adults expressing Rab14S49N.Scer\UAS.P\T.T:Avic\GFP-YFP under the control of either Scer\GAL4Hml.Δ or Scer\GAL4Act.PU show significantly decreased survival compared to controls after injection with S. aureus.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The formation of giant autophagic bodies in the retina of adult flies expressing Hsap\MAPTGMR.Ex.PJ is not suppressed by co-expression of Rab14S49N.Scer\UAS.P\T.T:Avic\GFP-YFP under the control of Scer\GAL4GMR.PU.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Rab14S49N.Scer\UAS.P\T.T:Avic\GFP-YFP
Rab14S49N.UASp.YFP
Name Synonyms
Secondary FlyBase IDs
    References (5)