FB2025_01 , released February 20, 2025
Allele: Avic\GFPGr5a.3x.IRES.2x
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General Information
Symbol
Avic\GFPGr5a.3x.IRES.2x
Species
A. victoria
Name
FlyBase ID
FBal0215569
Feature type
allele
Associated gene
Avic\GFP
Associated Insertion(s)
Carried in Construct
P{Gr5a-GFP.IRES.GFP.IRES.GFP}
Also Known As
Gr5a-GFP-IRES-GFP-IRES-GFP, Gr5a-I-GFP
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Fischler et al., 2007)
Progenitor genotype
Carried in construct
P{Gr5a-GFP.IRES.GFP.IRES.GFP}
Cytology
Description

Gr5a regulatory sequences drive expression of 3 copies of GFP separated by IRES sequences.

(Fischler et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Gr5a
Encoded product / tool
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      gustatory receptor neuron of labellar taste peg | subset
      (Fischler et al., 2007)
      gustatory receptor neuron | subset of adult gnathal ganglion
      (Fischler et al., 2007)
      sugar-sensing neuron of taste bristle
      (Cameron et al., 2010)
      gustatory receptor neuron | subset of labellar taste bristle
      (Cameron et al., 2010)
      gustatory receptor neuron of the labellum | subset of posterior maxillary sensory center
      (Miyazaki and Ito, 2010)
      Additional Information
      Statement
      Reference

      AvicGFPGr5a.3x.IRES.2x labels the sugar-sensing neurons (S cell) of the taste bristles of the proboscis. Neurons labeled with AvicGFPGr5a.3x.IRES.2x do not overlap with expression of ScerGAL4ppk28.PC, which labels the water-sensing neurons.

      (Cameron et al., 2010)

      AvicGFPGr5a.3x.IRES.2x is expressed in a subset of sugar-responsive gustatory receptor neurons of the labellum that project to regions PMS4 and PMS5 of the posterior maxillary sensory center. The projections pattern overlaps with the one of ScerGAL4NP1017.

      (Miyazaki and Ito, 2010)

      AvicGFPGr5a.3x.IRES.2x is expressed in the sugar-sensitive gustatory receptor neurons of the labellar taste pegs of the proboscis. Expression of AvicGFPGr5a.3x.IRES.2x in the proboscis is distinct from the expression of ScerGAL4E409. The projection of the neurons labeled by AvicGFPGr5a.3x.IRES.2x in the anterior subesophageal ganglion does not overlap with the projections labeled by ScerGAL4E409.

      (Fischler et al., 2007)
       
      Marker for
      sugar-sensing neuron of taste bristle
      (Cameron et al., 2010)
      Reflects expression of
      Gr5a
      (Cameron et al., 2010, Miyazaki and Ito, 2010, Fischler et al., 2007)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Avic\GFPGr5a.3x.IRES.2x
      Avic\GFPTre.3x.IRES.2x
      Name Synonyms
      Secondary FlyBase IDs
        References (7)