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General Information
Symbol
Mmus\Pnpla6UAS.cMa
Species
M. musculus
Name
FlyBase ID
FBal0215614
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Mmus\Pnpla6 coding sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Co-expression of Mmus\NTEScer\UAS.cMa significantly suppresses vacuolization of the lamina cortex in 14 day old flies with swsGD3277 driven by Scer\GAL4loco.PU.

Neuronal expression of Mmus\NTEScer\UAS.cMa, under the control of Scer\GAL4elav-C155 rescues some aspects of the neuronal degeneration, namely the vacuolisation in the neuropil.

Glial expression of Mmus\NTEScer\UAS.cMa, under the control of Scer\GAL4loco.1.3 rescues the glial phenotype.

Expression of Mmus\NTEScer\UAS.cMa in either neurons or glia (under the control of either Scer\GAL4elav-C155 or Scer\GAL4loco.1.3) restores the wild-type NTE-like activity (NTE-neuropathy target esterase).

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Mmus\NTEScer\UAS.cMa
Mmus\Pnpla6Scer\UAS.cMa
Mmus\Pnpla6UAS.cMa
Name Synonyms
Secondary FlyBase IDs
    References (2)