FB2025_01 , released February 20, 2025
Allele: Dmel\LanB1EP-600
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General Information
Symbol
Dmel\LanB1EP-600
Species
D. melanogaster
Name
FlyBase ID
FBal0216002
Feature type
allele
Associated gene
Dmel\LanB1
Associated Insertion(s)
P{GSV1}LanB1EP-600
Carried in Construct
Also Known As
EP-600, UAS-LanB1EP-600
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Urbano et al., 2009)
Progenitor genotype
Associated Insertion(s)
P{GSV1}LanB1EP-600
Cytology
Description

P{GSV1}LanB1EP-600 is inserted 548bp upstream of the 5'UTR of the LanB1 gene.

(Urbano et al., 2009)
Allele components
Component
Use(s)
Inserted element
P{GSV1}
Regulatory region(s)
UASt
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of EP-600EP-600 under the control of Scer\GAL4dpp.3KK results in wing vein thickening.

      Expression of EP-600EP-600 under the control of Scer\GAL4MD-638 results in wing vein thickening and strong loss of wing margin.

      Expression of EP-600EP-600 under the control of Scer\GAL4sca-C253 results in extra bristles.

      (Molnar et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      LanB1EP-600, Scer\GAL4GMR.PFa is a suppressor of eye phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4GMR.PFa

      (Catterson et al., 2023)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a P{GSV1} insertion line that when expressed using Scer\GAL4dpp.3KK results in a mutant phenotype in the wing.

      (Molnar et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP-600EP-600
      LanB1EP-600
      Name Synonyms
      Secondary FlyBase IDs
        References (4)