FB2025_01 , released February 20, 2025
Allele: Dmel\tayEP-866
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General Information
Symbol
Dmel\tayEP-866
Species
D. melanogaster
Name
FlyBase ID
FBal0216183
Feature type
allele
Associated gene
Dmel\tay
Associated Insertion(s)
P{GSV1}tayEP-866
Carried in Construct
Also Known As
EP-866
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV1}tayEP-866
    Cytology
    Description

    Insertion within CG9056.

    (Molnar et al., 2006)
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV1}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of tayEP-866 under the control of any of Scer\GAL4nub-AC-62, Scer\GAL4salm.EPv or Scer\GAL4dpp.3KK results in a reduction in the wing size and partial loss of longitudinal veins. The same phenotype is seen when tayEP-866 is expressed under the control of either Scer\GAL4ap-md544 or Scer\GAL4hh-Gal4.

        Flies expressing tayEP-866 under the control of Scer\GAL4Dll-md23 exhibit fusion of the tarsal joints.

        Flies expressing tayEP-866 under the control of Scer\GAL4ey.PU show a significant reduction in the size of the eye.

        Flies expressing tayEP-866 under the control of Scer\GAL4ap-md544 exhibit loss of sensory organs in the thorax.

        (Molnar and de Celis, 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhanced by
        Statement
        Reference

        Scer\GAL4nub-AC-62, tayEP-866 has visible phenotype, non-enhanceable by Mkp3M76-R2b

        (Molnar and de Celis, 2013)
        NOT suppressed by
        Statement
        Reference

        Scer\GAL4nub-AC-62, tayEP-866 has visible phenotype, non-suppressible by Mkp3M76-R2b

        (Molnar and de Celis, 2013)
        Enhancer of
        NOT Enhancer of
        Suppressor of
        NOT Suppressor of
        Phenotype Manifest In
        NOT Enhanced by
        Statement
        Reference

        Scer\GAL4nub-AC-62, tayEP-866 has wing phenotype, non-enhanceable by Mkp3M76-R2b

        (Molnar and de Celis, 2013)

        Scer\GAL4nub-AC-62, tayEP-866 has wing vein phenotype, non-enhanceable by Mkp3M76-R2b

        (Molnar and de Celis, 2013)
        NOT suppressed by
        Statement
        Reference

        Scer\GAL4nub-AC-62, tayEP-866 has wing phenotype, non-suppressible by Mkp3M76-R2b

        (Molnar and de Celis, 2013)

        Scer\GAL4nub-AC-62, tayEP-866 has wing vein phenotype, non-suppressible by Mkp3M76-R2b

        (Molnar and de Celis, 2013)
        Enhancer of
        NOT Enhancer of
        Suppressor of
        NOT Suppressor of
        Statement
        Reference

        tayEP-866, Scer\GAL4salm.EPv is a non-suppressor of wing vein phenotype of Mkp3UAS.Tag:MYC, Scer\GAL4salm.EPv

        (Molnar and de Celis, 2013)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Expression of tayEP-866 enhances the wing vein phenotype seen when EgfrNIG.10079R is expressed under the control of Scer\GAL4salm.EPv.

        Expression of tayEP-866 suppresses the ectopic wing vein phenotype seen when Ras85DV12.UAS is expressed under the control of Scer\GAL4salm.EPv.

        Expression of tayEP-866 does not modify the wing vein loss phenotype seen when Mkp3UAS.Tag:MYC is expressed under the control of Scer\GAL4salm.EPv.

        A Mkp3M76-R2b mutant background does not modify the loss of wing veins and reduction in wing size seen when tayEP-866 is expressed in the entire wing blade and hinge under the control of Scer\GAL4nub-AC-62.

        Expression of tayEP-866 partially suppresses the ectopic wing vein phenotype seen when rlSem.cUa.UAS is expressed under the control of Scer\GAL4salm.EPv.

        (Molnar and de Celis, 2013)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        tayEP-866 is rescued by tayRNAi.UAS/Scer\GAL4salm.EPv

        (Molnar and de Celis, 2013)

        tayEP-866 is rescued by tayRNAi.UAS/Scer\GAL4dpp.3KK

        (Molnar and de Celis, 2013)
        Comments

        Expression of taydsRNA.Scer\UAS suppresses the wing size reduction and loss of veins observed when tayEP-866 is expressed under the control of either Scer\GAL4salm.EPv or Scer\GAL4dpp.3KK.

        (Molnar and de Celis, 2013)
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer

        Selected as: a P{GSV1} insertion line that when expressed using Scer\GAL4dpp.3KK results in a mutant phenotype in the wing.

        (Molnar et al., 2006)

        Associated with: shiEP-866.

        (Molnar et al., 2006)

        Associated with: CG15916EP-866.

        (Molnar et al., 2006)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CG9056EP-866
        tayEP-866
        Name Synonyms
        Secondary FlyBase IDs
          References (2)