FlyBase Allele Report: Dmel\hppy[UAS.cMa]

General Information

Symbol

Dmel\hppy^UAS.cMa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Molnar

FlyBase ID

FBal0216185

Feature type

allele

Associated gene

Dmel\hppy

Associated Insertion(s)

Carried in Construct

P{UAS-hppy.M}

Key Links

Transgenic product class

cDNA

(Resnik-Docampo and de Celis, 2011)

wild_type

(Resnik-Docampo and de Celis, 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Resnik-Docampo and de Celis, 2011)

wild_type

(Resnik-Docampo and de Celis, 2011)

Mutagen

in vitro construct

(Molnar et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-hppy.M}

Cytology

Description

UASt drives expression of the complete RH10407 hppy cDNA.

(Resnik-Docampo and de Celis, 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

hppy

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval fat body, with Scer\GAL4^ppl.PP

(Resnik-Docampo and de Celis, 2011)

wing, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

wing vein | ectopic, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Detailed Description

Statement

Reference

Wing size is reduced when hppy^Scer\UAS.cMa is expressed using Scer\GAL4^nub-AC-62. Both cell size and cell number are reduced compared to controls. These effects are more severe is flies that carry two copies of both hppy^Scer\UAS.cMaand Scer\GAL4^nub-AC-62; extra vein material is also produced in this case.

Expression of hppy^Scer\UAS.cMa using Scer\GAL4^en.PU results in a significant increase in the fraction of mitotic cells in the posterior compartment of the wing disc.

Expression of hppy^Scer\UAS.cMa using Scer\GAL4^nub-AC-62 or Scer\GAL4^ap-md544 results in a robust cell-autonomous apoptotic response in wing discs.

Expression of hppy^Scer\UAS.cMa with Scer\GAL4^ppl.PP causes the fusion of lipid vesicles in the fat body.

(Resnik-Docampo and de Celis, 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell number phenotype, enhanceable by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by Scer\GAL4^nub-AC-62/raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell number phenotype, enhanceable by Scer\GAL4^nub-AC-62/raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by Scer\GAL4^nub-AC-62/raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell number phenotype, enhanceable by Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by RagC-D^Q99L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by RagC-D^Q99L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by S6k^KQ.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by S6k^KQ.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by S6k^NIG.10539R, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by S6k^NIG.10539R, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by Scer\GAL4^nub-AC-62/puc^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell number phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell number phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, enhanceable by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Suppressed by

Statement

Reference

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has increased cell death | cell autonomous phenotype, suppressible by Scer\GAL4^nub-AC-62/puc^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has increased cell death | cell autonomous phenotype, suppressible by Diap1^UAS.cHa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, suppressible by S6k^TE.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, suppressible by S6k^TE.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, non-suppressible by Df(3L)H99/+

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, non-suppressible by Df(3L)H99/+

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has abnormal size phenotype, non-suppressible by Diap1^UAS.cHa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has decreased cell size phenotype, non-suppressible by Diap1^UAS.cHa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Enhancer of

Statement

Reference

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell number phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell size phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell number phenotype of Scer\GAL4^nub-AC-62, raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of RagC-D^Q99L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell number phenotype of RagC-D^Q99L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of S6k^KQ.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of S6k^NIG.10539R, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of RagA-B^T16N.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell number phenotype of RagA-B^T16N.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell size phenotype of RagA-B^T16N.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell size phenotype of Scer\GAL4^nub-AC-62, path^UAS.cGa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell size phenotype of Scer\GAL4^nub-AC-62, slif^UAS.cCa

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell number phenotype of Scer\GAL4^nub-AC-62, mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell size phenotype of Scer\GAL4^nub-AC-62, mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell number phenotype of Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell number phenotype of Scer\GAL4^nub-AC-62, mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of decreased cell size phenotype of Scer\GAL4^nub-AC-62, mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell size phenotype of Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Suppressor of

Statement

Reference

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is a suppressor of abnormal size phenotype of RagA-B^Q61L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is a suppressor of increased cell number phenotype of RagA-B^Q61L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is a suppressor of increased cell number phenotype of Scer\GAL4^nub-AC-62, path^UAS.cGa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is a suppressor of increased cell number phenotype of Scer\GAL4^nub-AC-62, slif^UAS.cCa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is a suppressor of abnormal size phenotype of Scer\GAL4^nub-AC-62, gig^GD1454

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is a suppressor of abnormal size phenotype of Pten^GD13500, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by Scer\GAL4^nub-AC-62/raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by RagC-D^Q99L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by S6k^KQ.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by S6k^NIG.10539R, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by Scer\GAL4^nub-AC-62/mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, enhanceable by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Suppressed by

Statement

Reference

Scer\GAL4^nub-AC-62, hppy^UAS.cMa has wing phenotype, suppressible by S6k^TE.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Enhancer of

Statement

Reference

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, raptor^NIG.4320R

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of RagC-D^Q99L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of S6k^KQ.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of S6k^NIG.10539R, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of Akt^GD1361, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of RagA-B^T16N.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, path^UAS.cGa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, slif^UAS.cCa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, mTor^NIG.5092R

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, mTor^TED.UAS

(Resnik-Docampo and de Celis, 2011)

Suppressor of

Statement

Reference

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, path^UAS.cGa

(Resnik-Docampo and de Celis, 2011)

Scer\GAL4^nub-AC-62/hppy^UAS.cMa is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, slif^UAS.cCa

(Resnik-Docampo and de Celis, 2011)

hppy^UAS.cMa, Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of RagA-B^Q61L.UAS, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Reduction of cell death, either via heterozygosis for Df(3L)H99 or by co-expression of th^Scer\UAS.cHa does not significantly rescue the small wing size or small wing cell size seen in hppy^Scer\UAS.cMa, Scer\GAL4^nub-AC-62 flies. In contrast, preventing cell death via co-expression of puc^Scer\UAS.cMa enhances the small wing of hppy^Scer\UAS.cMa, Scer\GAL4^nub-AC-62 flies.

Co-expression of th^Scer\UAS.cHa or puc^Scer\UAS.cMa suppresses the increased apoptosis and increased fraction of mitotic cells phenotypes seen in Scer\GAL4^nub-AC-62, hppy^Scer\UAS.cMa discs.

Co-expression of hppy^Scer\UAS.cMa rescues the large wing phenotype of Pten^GD13500, Scer\GAL4^nub-AC-62 flies. Wing size and the number of cells is more similar to over-expression of hppy^Scer\UAS.cMa alone, while the cell size phenotype is intermediate.

Co-expression of hppy^Scer\UAS.cMa rescues the large wing phenotype of gig^GD1454, Scer\GAL4^nub-AC-62 flies. Wing size is similar to over-expression of hppy^Scer\UAS.cMa alone.

Co-expression of hppy^Scer\UAS.cMa and Akt1^GD1361 using Scer\GAL4^nub-AC-62 results in a strong synergistic phenotype of reduced wing size and reduced cell size and number.

Co-expression of hppy^Scer\UAS.cMa and Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} using Scer\GAL4^nub-AC-62 results in a strong synergistic phenotype of reduced wing size and reduced cell size and number.

Co-expression of hppy^Scer\UAS.cMa and Tor^NIG.5092R using Scer\GAL4^nub-AC-62 results in a strong synergistic phenotype of reduced wing size and reduced cell size and number.

Co-expression of hppy^Scer\UAS.cMa and Tor^TED.Scer\UAS using Scer\GAL4^nub-AC-62 results in a strong synergistic phenotype of reduced wing size and reduced cell size and number.

Co-expression of hppy^Scer\UAS.cMa and raptor^NIG.4320R using Scer\GAL4^nub-AC-62 results in a strong synergistic phenotype of reduced wing size and reduced cell size and number.

Co-expression of hppy^Scer\UAS.cMa cancels the increase in wing size and wing cell number resulting from expression of RagA^{Q61L.Scer\UAS} using Scer\GAL4^nub-AC-62.

Co-expression of hppy^Scer\UAS.cMa enhances the decrease in wing size, wing cell number and wing cell size resulting from expression of RagA^{T16N.Scer\UAS} using Scer\GAL4^nub-AC-62.

Co-expression of RagC^{Q99L.Scer\UAS} enhances the small wing and decreased wing cell size phenotypes seen in hppy^Scer\UAS.cMa, Scer\GAL4^nub-AC-62 wings.

Co-expression of hppy^Scer\UAS.cMa in the path^Scer\UAS.cGa, Scer\GAL4^nub-AC-62 background results in wings with cell sizes, cell numbers and overall wing size similar to hppy^Scer\UAS.cMa, Scer\GAL4^nub-AC-62 wings.

Co-expression of hppy^Scer\UAS.cMa in the slif^Scer\UAS.cCa, Scer\GAL4^nub-AC-62 background results in wings with cell sizes, cell numbers and overall wing size similar to hppy^Scer\UAS.cMa, Scer\GAL4^nub-AC-62 wings.

Co-expression of S6k^TE.Scer\UAS diminishes the small wing and decreased wing cell size phenotypes seen in hppy^Scer\UAS.cMa, Scer\GAL4^nub-AC-62 wings.

Co-expression of S6k^KQ.Scer\UAS and hppy^Scer\UAS.cMa using Scer\GAL4^nub-AC-62 results in a moderately synergistic phenotype of reduced wing size and reduced cell size.

Co-expression of S6k^NIG.10539R and hppy^Scer\UAS.cMa using Scer\GAL4^nub-AC-62 results in a moderately synergistic phenotype of reduced wing size and reduced cell size.

(Resnik-Docampo and de Celis, 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG7097^Scer\UAS.cMa

hppy^Scer\UAS.cMa

hppy^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Molnar

Secondary FlyBase IDs

References (2)

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