Allele Dmel\t^+t10.3

General Information
Symbol	Dmel\t^+t10.3	Species	D. melanogaster
Name		FlyBase ID	FBal0216687
Feature type	allele	Associated gene	Dmel\t

Allele class
Mutagen	in vitro construct - genomic fragment
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - genomic fragment (Jeong et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference 10.3kb KpnI-AflII genomic fragment that includes the entire t region (including the t cis-regulatory element that is located in the non-coding region between Gr8a and CG15370), the CG15370 gene and part of the Gr8a gene. (Jeong et al., 2008)
Carried in construct	P{t^+t10.3} (Jeong et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference D.santomea males carrying one copy of t^+t10.3 have a small patch of male-specific pigmentation along the posterior edge and midline of the A6 segment and also a light narrow stripe in the A2-A5 segments (wild-type D.santomea males lack all abdominal pigmentation). D.santomea males carrying two copies of of t^+t10.3 have more robust pigmentation; the A6 segment is pigmented more laterally and the pigmented stripes are wider in segments A2-A5. Compared to wild-type D.santomea females, which have light stripes of pigment in segments A2-A5 and no pigmentation in A6, D.santomea females carrying two copies of t^+t10.3 show robust pigmentation in a striped pattern in segments A2-A6. (Jeong et al., 2008)
Complementation & Rescue Data
Rescues	t^+t10.3 rescues t⁵ (Jeong et al., 2008)
Comments	t^+t10.3 rescues the abdominal pigmentation phenotype of t⁵ males. (Jeong et al., 2008)
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Assayed in D.melanogaster and in D.santomea. (Jeong et al., 2008)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	t^+t10.3
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Jeong et al., 2008, Cell 132(5): 783--793 The evolution of gene regulation underlies a morphological difference between two Drosophila sister species. [FBrf0203102]

Allele Dmel\t+t10.3

Allele Dmel\t^+t10.3