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General Information
Symbol
Dmel\Torey.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0217428
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Four copies of the eye-specific enhancer fragment from the ey gene and a noninducible heat-shock promoter regulate expression of Tag:FLAG-tagged Tor coding sequence.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Torey.hs.T:Zzzz\FLAG expression leads to an overall reduction in the size of the adult eye. Ommatidial patterning is disorganised, with some ommatidia appearing fused or pitted.

Torey.hs.T:Zzzz\FLAG eye imaginal discs experience a delay in morphogenetic furrow progression and missing and disorganised photoreceptor cells, as well as an increased level of cell death.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

Torey.Tag:FLAG has eye phenotype, enhanceable by Tsc129/Tsc1[+]

Torey.Tag:FLAG has eye phenotype, enhanceable by Hsc70-4e3/Hsc70-4[+]

Torey.Tag:FLAG has eye phenotype, enhanceable by Hsc70-4e19/Hsc70-4[+]

Suppressed by
Statement
Reference

Hsc70-4e19/Hsc70-4[+], Torey.Tag:FLAG has eye phenotype, suppressible by Hsc70-4+t14

Hsc70-4e3/Hsc70-4[+], Torey.Tag:FLAG has eye phenotype, suppressible by Hsc70-4+t14

Additional Comments
Genetic Interactions
Statement
Reference

The severity of the Torey.hs.T:Zzzz\FLAG phenotype is strongly enhanced by a heterozygous Tsc129 background and is suppressed by addition of rapamycin to the media.

Expression of shiK44A.Scer\UAS (under the control of Scer\GAL4ey.PH) strongly enhances the Torey.hs.T:Zzzz\FLAG phenotype.

Heterozygous Hsc70-4e3 mutants cause a further reduction in eye size of Torey.hs.T:Zzzz\FLAG mutants.

Heterozygous Hsc70-4e19 mutants cause a further reduction in eye size of Torey.hs.T:Zzzz\FLAG mutants.

The presence of Hsc70-4+t14 suppresses enhancement of the Torey.hs.T:Zzzz\FLAG eye phenotype by Hsc70-4e3 or Hsc70-4e19.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Torey.Tag:FLAG
Torey.hs.T:Zzzz\FLAG
Name Synonyms
Secondary FlyBase IDs
    References (1)