Allele Dmel\mre11^unspecified

General Information
Symbol	Dmel\mre11^unspecified	Species	D. melanogaster
Name		FlyBase ID	FBal0217452
Feature type	allele	Associated gene	Dmel\mre11

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| pupal stage (Bi et al., 2005)
Phenotype Manifest In
	chromosome & neuroblast \| third instar larval stage 2 (Bi et al., 2005)
Detailed Description
	Statement Reference The chromosomes of third instar larval neuroblasts of mre11^unspecified mutants frequently have fused ends. (Bi et al., 2005)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference mre11^unspecified has chromosome & neuroblast \| third instar larval stage 2 phenotype, enhanceable by mus304^D1/mus304^D1 (Bi et al., 2005)
NOT Enhanced by
Statement Reference mre11^unspecified has chromosome & neuroblast \| third instar larval stage 2 phenotype, non-enhanceable by grp⁰⁶⁰³⁴ (Bi et al., 2005) mre11^unspecified has chromosome & neuroblast \| third instar larval stage 2 phenotype, non-enhanceable by lok^p6 (Bi et al., 2005)
NOT Enhancer of
Statement Reference mre11^unspecified is a non-enhancer of chromosome & neuroblast \| third instar larval stage 2 phenotype of nbs¹ (Bi et al., 2005)
NOT Suppressor of
Statement Reference mre11^unspecified is a non-suppressor of chromosome & neuroblast \| third instar larval stage 2 phenotype of nbs¹ (Bi et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference mre11[unspecified] does not override the reduced mitotic index of sea[EP3364] single mutants. (Morciano et al., 2009) The chromosome fusion phenotype seen in the nuclei of third instar larval neuroblasts of mre11^unspecified mutants is enhanced by mus304^D1/mus304^D1 but not by grp⁰⁶⁰³⁴ or lok^p6. mre11^unspecified does not enhance or suppress the telomere fusion phenotype seen in third instar larval neuroblasts due to nbs¹. (Bi et al., 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	mre11^unspecified
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Morciano et al., 2009, Hum. Mol. Genet. 18(21): 4180--4188 A conserved role for the mitochondrial citrate transporter Sea/SLC25A1 in the maintenance of chromosome integrity. [FBrf0209145] Bi et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(42): 15167--15172 Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance. [FBrf0191425]

Allele Dmel\mre11unspecified

Allele Dmel\mre11^unspecified