Allele Dmel\Dscam^{7.27.25.1.Scer\UAS.cZa}

General Information
Symbol	Dmel\Dscam^{7.27.25.1.Scer\UAS.cZa}	Species	D. melanogaster
Name		FlyBase ID	FBal0217462
Feature type	allele	Associated gene	Dmel\Dscam

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Zhan et al., 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of a Dscam isoform which contains the alternative exons 4.7, 6.27, 9.25 and 17.1. (Zhan et al., 2004)
Carried in construct	P{UAS-Dscam.7.27.25.1.Z} (Zhan et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective, with Scer\GAL4^elav-C155 (Zhan et al., 2004)
Phenotype Manifest In
	adult mushroom body, with Scer\GAL4^elav-C155 (Zhan et al., 2004) lobe system of mushroom body, with Scer\GAL4^elav-C155 (Zhan et al., 2004)
Detailed Description
	Statement Reference Expression of Dscam^{7.27.25.1.Scer\UAS.cZa} under the control of Scer\GAL4^elav-C155 in large mushroom body clones in a wild-type background results in defects in the mushroom body, including disorganised lobes and ectopic projections of axons outside the mushroom body neuropil into adjacent brain regions. (Zhan et al., 2004)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	Scer\GAL4^elav-C155/Dscam^{7.27.25.1.Scer\UAS.cZa} fails to rescue Dscam^unspecified (Zhan et al., 2004)
Comments	The branch segregation defects seen in homozygous Dscam^unspecified clones in the mushroom body are not rescued by expression of Dscam^{7.27.25.1.Scer\UAS.cZa} under the control of Scer\GAL4^elav-C155. (Zhan et al., 2004)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Dscam^{7.27.25.1.Scer\UAS.cZa}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Zhan et al., 2004, Neuron 43(5): 673--686 Analysis of Dscam diversity in regulating axon guidance in Drosophila mushroom bodies. [FBrf0180574]

Allele Dmel\Dscam7.27.25.1.Scer\UAS.cZa

Allele Dmel\Dscam^{7.27.25.1.Scer\UAS.cZa}