Allele Dmel\Hip14³

General Information
Symbol	Dmel\Hip14³	Species	D. melanogaster
Name		FlyBase ID	FBal0217483
Feature type	allele	Associated gene	Dmel\Hip14

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Ohyama et al., 2007)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: C432@. (Ohyama et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| pupal stage (with Df(3L)brm11) (Ohyama et al., 2007) lethal \| pupal stage (with Hip14¹) (Ohyama et al., 2007) lethal \| pupal stage (with Hip14²) (Ohyama et al., 2007) neurophysiology defective \| somatic clone (Ohyama et al., 2007)
Phenotype Manifest In
	retina \| somatic clone (Ohyama et al., 2007) synapse & eye photoreceptor cell \| somatic clone (Ohyama et al., 2007)
Detailed Description
	Statement Reference The electroretinograms (ERGs) of flies in which the eyes are composed of homozygous tissue are abnormal; they lack the on and off transients, but depolarisation is normal. Ultrastructural analysis of mutant photoreceptor synapses in the lamina (in flies in which the eyes are composed of homozygous tissue) shows that capitate projections are often shallow in mutants compared with controls. (Ohyama et al., 2007)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	Hip14²/Hip14³ is rescued by Hip14^+t6.5 (Ohyama et al., 2007) Hip14²/Hip14³ is rescued by Scer\GAL4^elav-C155/Hip14^Scer\UAS.cOa (Ohyama et al., 2007) Hip14³/Hip14¹ is rescued by Hip14^+t6.5 (Ohyama et al., 2007)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer
	Associated with: a separable lethal mutation on the chromosome; homozygotes show third larval instar lethality in comparison to the late pupal lethality of transheterozygotes with Hip14¹, and the homozygous lethality is not rescued by Hip14^+t6.5 (whereas the transheterozygous lethality is rescued by Hip14^+t6.5). (Ohyama et al., 2007)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	3L1³ (Ohyama et al., 2007) Hip14³ hip14³ (Ohyama et al., 2007)
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Ohyama et al., 2007, J. Cell Biol. 179(7): 1481--1496 Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles. [FBrf0200919]

Allele Dmel\Hip143

Allele Dmel\Hip14³