FB2020_06, released Dec 22, 2020

Allele: Dmel\AbiUAS.Tag:Myr(Src64B)

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General Information
Symbol
Dmel\AbiUAS.Tag:Myr(Src64B)
Species
D. melanogaster
Name
FlyBase ID
FBal0217582
Feature type
allele
Associated gene
Dmel\Abi
Associated Insertion(s)
Carried in Construct
P{UAS-Abi.Myr}
Also Known As
UAS-AbiMyr
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Bogdan et al., 2005)
in vitro construct - coding region fusion
(Bogdan et al., 2005)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-Abi.Myr}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UAS regulatory sequence drive expression of Abi that is tagged with a myristoylation signal (Tag:Myr(Src64B)).

      (Bogdan et al., 2005)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      Abi
      Tagged with
      Tag:Myr(Src64B)
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of AbiScer\UAS.T:Myr1 under the control of Scer\GAL4en-e16E in the posterior compartment of the third larval instar wing disc stimulates F-actin formation at the expense of the free G-actin pool.

      Expression of AbiScer\UAS.T:Myr1 under the control of Scer\GAL4sca-537.4 results in extra bristles on the notum. The flies have extra notopleural bristles.

      Expression of AbiScer\UAS.T:Myr1 under the control of Scer\GAL4sca-537.4 results in the formation of additional sensory organ precursor cells in the wing imaginal disc.

      (Bogdan et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      AbiUAS.Tag:Myr(Src64B), Scer\GAL4sca-537.4 has visible phenotype, suppressible | partially by WASp3

      (Bogdan et al., 2005)
      NOT suppressed by
      Statement
      Reference

      AbiUAS.Tag:Myr(Src64B), Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by SCARΔ37

      (Bogdan et al., 2005)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of WASpΔCA.Scer\UAS suppresses the ectopic F-actin formation seen when AbiScer\UAS.T:Myr1 is expressed under the control of Scer\GAL4en-e16E in the posterior compartment of the third larval instar wing disc.

      The extra notopleural bristles induced by expression of AbiScer\UAS.T:Myr1 under the control of Scer\GAL4sca-537.4 can be partially suppressed by WASp3, but are not suppressed by SCARΔ37.

      (Bogdan et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      AbiScer\UAS.T:Myr-Src64B
      AbiScer\UAS.T:Myr1
      AbiUAS.Tag:Myr(Src64B)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)