FB2025_01 , released February 20, 2025
Allele: Dmel\trplninaE.EGFP
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General Information
Symbol
Dmel\trplninaE.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0217602
Feature type
allele
Associated gene
Dmel\trpl
Associated Insertion(s)
Carried in Construct
P{Rh1-trpl-eGFP}
Also Known As
trpl-eGFP
Key Links
Transgenic product class
wild_type
(Meyer et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Meyer et al., 2006)
Mutagen
in vitro construct
(Meyer et al., 2006)
Progenitor genotype
Carried in construct
P{Rh1-trpl-eGFP}
Cytology
Description

A DNA construct containing the ninaE promoter upstream of trpl coding sequences fused with EGFP sequences.

(Meyer et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
Encoded product / tool
trpl
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ERG-recordings from trplninaE.T:Avic\GFP-EGFP-expressing mutants reveals responses to medium intensity lights, which decline to that of the dark baseline during illumination, within 5 seconds. This light response is very different to wild-type flies, which have a sustained response during illumination and the response to the first and second light pulses are virtually identical. Intensity-response relationships (V-log I curves) of trplninaE.T:Avic\GFP-EGFP-expressing mutants mutants are shifted to higher levels of light intensity by about 1 log unit as compared to wild-type flies. Responses of trplninaE.T:Avic\GFP-EGFP-expressing mutants to a second light pulse are significantly lager than in wild-type.

      (Meyer et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      trplninaE.EGFP
      trplninaE.T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (8)