Small deletion that removes the sixth exon, resulting in a deletion of 76 amino acids (residues 482 to 558).
Homozygous clones in the wing result in abnormal wing hairs, with a range of phenotypes being seen. The most extremely affected cells show multiple blebs and ridges, while less affected cells have hairs that are wider, often bent and occasionally split. Homozygous clones in the wing occasionally produce with multiple wing hairs or a fair of obvious abnormal polarity.
Homozygous clones in the pupal wing show a dramatic cell-autonomous increase in the level of F-actin compared to wild type, and this increase is seen both prior to and during wing hair morphogenesis.
Mean clone size in the adult wing is smaller when clones are induced at 3-4 days after egg laying (AEL) compared to 4-5 days AEL, indicating that homozygous cells are lost over time. Almost no clones are recovered in adult wings when they are induced at 2-3 days AEL.
flr5/flr6 is partially rescued by Scer\GAL4Act.PU/flrUAS.GFP