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General Information
Symbol
Dmel\subATP.UASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0218569
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: G152A.

UASp regulatory sequences drive expression of a mutated form of sub, which has a mutated ATP-binding domain, and which is tagged with Tag:HA.

Amino acid replacement: K153A.

Amino acid replacement: T154A.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

spindle microtubule & oocyte, with Scer\GAL4VP16.nos.UTR

Detailed Description
Statement
Reference

Females expressing subATP.Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 show a high rate of nondisjunction. The meiotic spindles of oocytes in these females show abnormal, albeit, mild defects in microtubule organisation, with spindles that are frayed, unusually curved, lack interpolar microtubules or have asymmetries such as large knob structures.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
subATP.Scer\UAS.P\T.T:Ivir\HA1
subATP.UASp.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (1)