Expression of GSd211GSd211 under the control of Scer\GAL4109(2)80 results in defects in the dendrites of dorsal cluster dendritic arborisation (da) neurons in third instar larvae: dendrite morphology is defective in the class I and class III da neurons, dendrite growth is reduced in the class II da neurons and dendrite growth and branching are reduced in the class IV da neurons.
Isolated RP2 neuron clones expressing GSd211GSd211 under the control of Scer\GAL4Act5C.PP (clones generated using the Scer\FLP1eve.RN2 line) show a reduction in dendrite growth at 25-31 hours after egg laying. The distribution of dendrites in the dendritic field is altered: there is a decrease in the number of dendrites targeted to the anterior, posterior, medial and lateral regions of the dendritic field.
Fas2-positive axon bundles in the ventral nerve cord are missing or disrupted in embryos expressing GSd211GSd211 under the control of Scer\GAL4scrt-11-6. In the periphery, the ISNb, ISNd, SNa and SNc motor neurons are missing or thinned.