FB2025_01 , released February 20, 2025
Allele: Dmel\GSd402GSd402
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General Information
Symbol
Dmel\GSd402GSd402
Species
D. melanogaster
Name
FlyBase ID
FBal0218632
Feature type
allele
Associated gene
GSd402
Associated Insertion(s)
P{GSV1}GSd402GSd402
Carried in Construct
Also Known As
GSd402
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV1}GSd402GSd402
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV1}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of GSd402GSd402 under the control of Scer\GAL4109(2)80 results in severe reduction of dendrite outgrowth and branching in the dendrites of dorsal cluster dendritic arborisation (da) neurons in third instar larvae (class I, II, III and IV da neurons are all affected), often accompanied by degeneration of the cell soma.

        (Ou et al., 2008)

        Fas2-positive axon bundles in the ventral nerve cord are missing or disrupted in embryos expressing GSd402GSd402 under the control of Scer\GAL4scrt-11-6. In the periphery, the SNa and SNc motor neurons are missing or thinned, while the ISNb and ISNd motor neurons are thickened.

        (Minidorff et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        GSd402
        (Ou et al., 2008)
        GSd402GSd402
        Name Synonyms
        Secondary FlyBase IDs
          References (3)