FB2025_01 , released February 20, 2025
Allele: Dmel\GSd433GSd433
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General Information
Symbol
Dmel\GSd433GSd433
Species
D. melanogaster
Name
FlyBase ID
FBal0218675
Feature type
allele
Associated gene
GSd433
Associated Insertion(s)
P{GSV1}GSd433GSd433
Carried in Construct
Also Known As
GSd433
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV1}GSd433GSd433
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV1}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Isolated RP2 neuron clones expressing GSd433GSd433 under the control of Scer\GAL4Act5C.PP (clones generated using the Scer\FLP1eve.RN2 line) show altered distribution of dendrites in the dendritic field at 25-31 hours after egg laying: the number of dendrites targeted to anterior regions is decreased, the number targeted to posterior regions is increased, the number targeted to medial regions is decreased and the number targeted to lateral regions is increased.

        (Ou et al., 2008)

        Several defects are seen in Fas2-positive axon bundles of the ventral nerve cord in embryos expressing GSd433GSd433 under the control of Scer\GAL4scrt-11-6; missing or disrupted axon bundles, axon bundles that are diffuse or less distinct than normal and axons crossing the midline are seen. In the periphery, the SNa motor neuron is missing or thinned, while the ISNb, ISNd and SNc motor neurons are thickened.

        (Minidorff et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        GSd433
        (Ou et al., 2008)
        GSd433GSd433
        Name Synonyms
        Secondary FlyBase IDs
          References (3)