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General Information
Symbol
Dmel\Stam2L3297
Species
D. melanogaster
Name
FlyBase ID
FBal0219180
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:
T10860668C
Reported nucleotide change:
T1283C
Amino acid change:
F428S | Stam-PA
Reported amino acid change:
F428S
point mutation
Nucleotide change:
T10861033C
Reported nucleotide change:
T1583C
Amino acid change:
Y528H | Stam-PA
Reported amino acid change:
Y528H
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Amino acid replacement: F428S.
Nucleotide substitution: T1283C.
Amino acid replacement: Y528H.
Nucleotide substitution: T1583C.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Somatic clones of Stam2L3297/Stam2L3297 cells in the third instar larval eye or wing disc display low levels of apoptosis (detected by Caspase-3 staining).
Homozygous clones show defects in tracheal cell migration during morphogenesis of the dorsal air sac primordium; less than 40% of clones reach the distal tip of the primordium.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Enhancer of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Somatic clones of Rbf15aΔ;Stam2L3297 double homozygous cells display significantly higher levels of apoptosis in third instar larval wing and eye discs, even in clones posterior to the eye disc morphogenetic furrow, compared to clones homozygous for either Rbf15aΔ or Stam2L3297 alone.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)