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General Information
Symbol
Dmel\Stam2L2896
Species
D. melanogaster
Name
FlyBase ID
FBal0219181
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
stam2896
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:
G10860898A
Reported nucleotide change:
G1513A
Amino acid change:
A505T | Stam-PA
Reported amino acid change:
A505T
point mutation
Nucleotide change:
C10858850T
Reported nucleotide change:
C16T
Amino acid change:
Q6term | Stam-PA
Reported amino acid change:
Q6term
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Nucleotide substitution: C16T.
Amino acid replacement: A505T.
Nucleotide substitution: G1513A.
Amino acid replacement: Q6term.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Homozygous mushroom body gamma neuron clones show normal axon pruning.
Stam2L2896 follicular epithelium clones display normal epithelial morphology. There is no detectable phenotype in Stam2L2896 mosaic eye imaginal discs or imaginal discs consisting predominantly of mutant cells. Eye discs consisting predominantly of cells mutant for Stam2L2896 progress to form adult eyes. These are smaller than wild-type and have a rough appearance but contain some mutant photoreceptors. The scarcity of mutant adult photoreceptors might be due to cell death, as apoptotic cells are seen these mutants.
Homozygous clones show defects in tracheal cell migration during morphogenesis of the dorsal air sac primordium; less than 40% of clones reach the distal tip of the primordium.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
HrsD28/HrsD28 Stam2L2896/Stam2L2896 MARCM ddaC double mutant clones show dendrite pruning similar to wild type at 18hr APF.
HrsD28 Stam2L2896 double homozygous mushroom body gamma neuron clones show defects in axon pruning.
HrsD28 Stam2L2896 follicular epithelium clones display normal epithelial morphology. HrsD28 Stam2L2896 l(2)gl4 follicular epithelium clones display normal epithelial morphology.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (6)