Allele Dmel\nkd^{ΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP}

General Information
Symbol	Dmel\nkd^{ΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0219571
Feature type	allele	Associated gene	Dmel\nkd

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Chan et al., 2008) in vitro construct - regulatory fusion (Chan et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of an internally deleted form of nkd (amino acids 179-370, 424-466 and 543-572 are missing) which is tagged at the C-terminal end with T:Avic\GFP[EGFP]. (Chan et al., 2008)
Carried in construct	P{UAS-nkd.ΔR1SΔD6Δ30aa.GFPC} (Chan et al., 2008)
Tagged with	T:Avic\GFP^EGFP (Chan et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	Scer\GAL4^da.G32/nkd^{ΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP} fails to rescue nkd³ (Chan et al., 2008)
Comments	Expression of nkd[ΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP] under the control of Scer\GAL4[da.G32] fails to rescue the nkd[3] embryonic cuticle phenotype. (Chan et al., 2008)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Nkd^{ΔR1SΔD6Δ30aa/GFPC} (Chan et al., 2008) nkd^{ΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Chan et al., 2008, Dev. Biol. 318(1): 17--28 Drosophila Naked cuticle (Nkd) engages the nuclear import adaptor Importin-alpha3 to antagonize Wnt/beta-catenin signaling. [FBrf0205127]

Allele Dmel\nkdΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP

Allele Dmel\nkd^{ΔR1SΔD6Δ30aa.Scer\UAS.T:Avic\GFP-EGFP}