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General Information
Symbol
Dmel\MycJF01761
Species
D. melanogaster
Name
FlyBase ID
FBal0219810
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of MycJF01761 RNAi under the control of Scer\GAL4ap.PU does not increase levels of cell death (detected by Casp3 antibody staining) in third instar larval wing discs compared to controls.
Expression of MycJF01761 in the fat body under the control of Scer\GAL4DcG results in significant hyperglycaemia. Expression of MycJF01761 in muscle under the control of Scer\GAL4Mef2.PU results in significant hyperglycaemia.
Expression of MycJF01761 under the control of Scer\GAL4bs-1348 results in the truncation of terminal branches in the dorsal and lateral G branches of the larval trachea.
Larval fat body cell clones expressing dmJF01761 display fewer digesting autolysosomes than do wild-type cells. Fat body cell clones expressing dmJF01761 in well-fed larvae show cell-autonomous impairment of autophagy.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
The Malpighian tubules deformities characteristic for BicC5 homozygous mutant adults are partially rescued by expression of MycJF01761 under the combined control of Scer\GAL4c42 and Scer\GAL4tsh-c724 drivers: the incidence of cysts is significantly reduced in the terminal and in the proximal tubule, the tubular swelling and the irregular distribution of cell nuclei is also reduced compared to controls.
The increased level of cell death (detected by Casp3 antibody staining) observed in wing discs of third instar larvae expressing REGKK102083 RNAi under the control of Scer\GAL4ap.PU is partially suppressed by co-expression of MycJF01761 RNAi.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
MycJF01761
Myc[JF01761]
Myc[i, JF01761]
dmJF01761
Name Synonyms
Secondary FlyBase IDs
    References (10)