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General Information
Symbol
Dmel\SharkJF01794
Species
D. melanogaster
Name
FlyBase ID
FBal0219815
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of SharkJF01794 in muscle under the control of Scer\GAL4Mef2.PU results in significant hyperglycaemia.
Under normal nutritional conditions egg chambers from flies expressing sharkJF01794 under the control of Scer\GAL4GR1 develop normally through mid-oogenesis. However, when degenerating egg chambers are induced by starvation the mutant flies show significant defects in the normal engulfment of dying germline cells. Unlike in wild type, the follicle cells fail to enlarge as nurse cell chromatin condenses and minimal uptake of nuclear fragments is seen. As egg chamber death progresses, the follicle cells die without clearing most of the nurse cell debris.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
SharkJF01794
sharkJF01794
Name Synonyms
Secondary FlyBase IDs
    References (3)