Allele Dmel\Nup160^e00704

General Information
Symbol	Dmel\Nup160^e00704	Species	D. melanogaster
Name		FlyBase ID	FBal0220491
Feature type	allele	Associated gene	Dmel\Nup160

Map ( GBrowse )	Untitled Document
Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2L:11,128,949..11,128,949 (Tang and Presgraves, 2009, Sawamura et al., 2010, Maehara et al., 2012)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	PBac{RB}RfC38^e00704 (Tang and Presgraves, 2009, Sawamura et al., 2010, Maehara et al., 2012)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Nup160[e00704] homozygotes are inviable. (Sawamura et al., 2010) Nup160[e00704] causes hybrid lethality in Dmel X Dsim males carrying a Dmel X chromosome and in Dmel X Dsim females carrying 2 Dmel X chromosomes (as the attached X C(1)A)Q1 This lethality is not seen in males or females of the same genotype apart from carrying a Dsim X, or in the progeny of wild-type Dmel X Dsim crosses. (Tang and Presgraves, 2009)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	Nup160^e00704 is rescued by Nup160^Scer\UAS.cTa/Scer\GAL4^tub.PU (Tang and Presgraves, 2009)
Comments	Dmel X Dsim hybrid male lethality due to Nup160[e00704] is rescued by Nup160[Scer\UAS.cTa]. (Tang and Presgraves, 2009)
Stocks ( 1 )
Harvard	- PBac{RB}RfC38^e00704
Notes on Origin
Discoverer

Comments
	Precise excision of PBac{RB}RfC38[e00704] reverts the hybrid male lethality of Nup160[e00704]/Dsim[+]. (Tang and Presgraves, 2009)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Nup160^e00704 (Maehara et al., 2012, )
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Maehara et al., 2012, Genes & Genet. Systems 87(2): 99--106 Genetic dissection of Nucleoporin 160 (Nup160), a gene involved in multiple phenotypes of reproductive isolation in Drosophila. [FBrf0218968] Sawamura et al., 2010, Genetics 186(2): 669--676 Introgression of Drosophila simulans nuclear pore protein 160 in Drosophila melanogaster alone does not cause inviability but does cause female sterility. [FBrf0212080] Tang and Presgraves, 2009, Science 323(5915): 779--782 Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities. [FBrf0206719]

Allele Dmel\Nup160e00704

Allele Dmel\Nup160^e00704