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General Information
Symbol
Dmel\Syx18JF02263
Species
D. melanogaster
Name
FlyBase ID
FBal0220653
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
JF02263
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing Syx18JF02263 under the control of Scer\GAL4pros-V1 results in larger late endosomes in larval garland cells (Rab7-positive puncta in fluorescence microscopy).

Clonal expression of Syx18JF02263 under the control of Scer\GAL4Act5C.PP (in combination with Dicer-2, for a more efficient RNAi) affects the distribution of autophagic vesicles in the larval fat body (Atg8-positive puncta in fluorescence microscopy).

Expressing Syx18JF02263 under the combined control of Scer\GAL4fkh.PH abolishes glue granules in the larval salivary glands; in agreement, all of the (pre)pupae fell down from the wall of the culture vials.

The expression of Syx18JF02263 under the control of Scer\GAL4SPARC-MI00329-GAL4 (and Dicer-2, for a more efficient RNAi) in the larval fat body induces defective secretion, including intracellular matrix material, as shown by the retention of both secr.GFP and Vkg.GFP.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Syx18JF02263
Name Synonyms
Secondary FlyBase IDs
    References (7)