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General Information
Symbol
Dmel\Mdr49δ3.16
Species
D. melanogaster
Name
FlyBase ID
FBal0220784
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Cytology
    Nature of the lesion
    Statement
    Reference

    Imprecise excision of P{}mdr49KG08611 has deleted 3.4kb flanking the insertion site.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Somatic gonadal precursors are normally specified in Mdr49δ3.16 homozygous embryos.

    Germ cells in Mdr49δ3.16 homozygous or Mdr49δ3.16/Df(2R)Exel7123 embryos migrate through the posterior midgut, but many then fail to associate with somatic gonadal precursors. The same phenotype, but with fewer germ cells affected, is seen in Mdr49δ3.16 heterozygotes and Mdr49δ3.16/Mdr49KG08611 embryos.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Ectopic migration of germ cells to the CNS in HmgcrScer\UAS.cvDa; Scer\GAL4elav-C155 embryos is partially suppressed by Mdr49KG08611/+.

    Xenogenetic Interactions
    Statement
    Reference

    The germ cell migration defects seen in Mdr49δ3.16 homozygous embryos are largely suppressed by Scer\STE6Scer\UAS,T:Avic\GFP; Scer\GAL4twi.PG.

    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (3)