Allele Dmel\Bx^hdp-n60

General Information
Symbol	Dmel\Bx^hdp-n60	Species	D. melanogaster
Name		FlyBase ID	FBal0220818
Feature type	allele	Associated gene	Dmel\Bx
Also Known As	hdpⁿ⁶⁰

Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Asmar et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{EP}Bx^G1515-2 (Asmar et al., 2008)
Nature of the lesion	Statement Reference Imprecise excision of the progenitor insertion, resulting in deletion that removes 1.8kb of Bx coding sequence spanning the two LIM domains. (Asmar et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	flightless (Asmar et al., 2008) viable (Asmar et al., 2008) visible (Biryukova et al., 2009, Asmar et al., 2008)
Phenotype Manifest In
	wing (Biryukova et al., 2009, Asmar et al., 2008)
Detailed Description
	Statement Reference Bx[hdp-n60] flies have erect wings with an almost wild-type shape. (Biryukova et al., 2009) Mutants have a mild held-up wing phenotype. (Asmar et al., 2008)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference Bx^hdp-n60 is an enhancer of visible \| dominant phenotype of pnr^VX4 (Asmar et al., 2008)
Suppressor of
Statement Reference Bx^hdp-n60 is a suppressor of visible \| dominant phenotype of Chi^e5.5 (Asmar et al., 2008) Bx^hdp-n60 is a suppressor of visible \| dominant phenotype of pnr^D1 (Asmar et al., 2008) Bx^hdp-n60 is a suppressor of visible phenotype of mir-9a^J22 (Biryukova et al., 2009)
NOT Suppressor of
Statement Reference Bx^hdp-n60 is a non-suppressor of visible phenotype of Chi^E (Asmar et al., 2008)
Other
Statement Reference Bx^hdp-n60, pnr[+]/pnr^VX6 has visible phenotype (Asmar et al., 2008)
Phenotype Manifest In
Enhancer of
Statement Reference Bx^hdp-n60 is an enhancer of dorsocentral bristle phenotype of pnr^VX4 (Asmar et al., 2008)
Suppressor of
Statement Reference Bx^hdp-n60 is a suppressor of dorsocentral bristle \| supernumerary phenotype of Chi^e5.5 (Asmar et al., 2008) Bx^hdp-n60 is a suppressor of dorsocentral bristle \| supernumerary phenotype of pnr^D1 (Asmar et al., 2008) Bx^hdp-n60 is a suppressor of wing margin phenotype of mir-9a^J22 (Biryukova et al., 2009)
NOT Suppressor of
Statement Reference Bx^hdp-n60 is a non-suppressor of adult thorax phenotype of Chi^E (Asmar et al., 2008) Bx^hdp-n60 is a non-suppressor of dorsocentral bristle phenotype of Chi^E (Asmar et al., 2008)
Other
Statement Reference Bx^hdp-n60, pnr[+]/pnr^VX6 has dorsocentral bristle phenotype (Asmar et al., 2008)
Additional Comments
Genetic Interactions
Statement Reference The loss of wing margin seen in mir-9a[J22] flies is completely suppressed by Bx[hdp-n60]. (Biryukova et al., 2009) The extra dorsocentral bristle phenotype seen in Chi[e5.5]/+ flies is suppressed if the flies are also hemizygous for Bx[hdp-n60]. The Chi[E] homozygous phenotype of loss of dorsocentral bristles and presence of a slight thoracic cleft is not modified by hemizygosity for Bx[hdp-n60]. Bx[hdp-n60]/Y ; pnr[VX6]/+ flies show loss of dorsocentral bristles. Bx[hdp-n60]/Y ; pnr[VX4]/+ flies show a severe loss of dorsocentral bristles (significantly more loss is seen than in pnr[VX4]/+ flies). The extra dorsocentral bristle phenotype seen in pnr[D1]/+ flies is suppressed by Bx[hdp-n60]/Y. (Asmar et al., 2008)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Bx^hdp-n60 hdpⁿ⁶⁰ (Biryukova et al., 2009, Asmar et al., 2008)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Biryukova et al., 2009, Dev. Biol. 327(2): 487--496 Drosophila mir-9a regulates wing development via fine-tuning expression of the LIM only factor, dLMO. [FBrf0207536] Asmar et al., 2008, Dev. Biol. 316(2): 487--497 Drosophila dLMO-PA isoform acts as an early activator of achaete/scute proneural expression. [FBrf0205286]

Allele Dmel\Bxhdp-n60

Allele Dmel\Bx^hdp-n60