FB2020_06, released Dec 22, 2020

Allele: Dmel\larp06487

Open Close
General Information
Symbol
Dmel\larp06487
Species
D. melanogaster
Name
FlyBase ID
FBal0220948
Feature type
allele
Associated gene
Dmel\larp
Associated Insertion(s)
P{PZ}larp06487
Carried in Construct
Genomic Maps
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    transposable element insertion site
    3R:28,326,512..28,326,512 [+]
    (Blagden et al., 2009, Ichihara et al., 2007)
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
         
        Progenitor genotype
        Cytology
        Nature of the lesion
        Statement
        Reference

        P{PZ} insertion in the first intron.

        (Ichihara et al., 2007)
        Insertion components
        P{PZ}larp06487
        Product class / Tool use(s)
        Encoded product / tool
        lacZ
        Tagged with
        Tag:NLS(P)
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        6% of larp06487/larpmtr-null females are sterile.

        (Blagden et al., 2009)

        31.4% of onion stage spermatids show abnormalities in larpmtr1/larp06487 males. Of these abnormal cells, 52.0% show abnormal cell numbers or size, 35.0% have abnormal Nebenkern numbers or size, 13.0% show a failure of cytokinesis and 3.4% have multiple abnormalities.

        (Ichihara et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer

        Separable from: l(3)0648706487.

        (Ichihara et al., 2007)

        The lethality of the "l(3)06487" chromosome (represented by l(3)0648706487) is separable from the P{PZ}larp06487 insertion within the larp gene.

        (Ichihara et al., 2007)
        Comments
        Comments

        Allelic series (severity of mutant alleles): larpmtr-null > larpS003108 > larpS022529 > larp06487.

        (Blagden et al., 2009)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        larp106487
        (Singh et al., 2011)
        larp06487
        larp<up>mtr 2</up>
        (Blagden et al., 2009)
        larpmtr2
        (Ichihara et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)