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General Information
Symbol
Dmel\elgi1
Species
D. melanogaster
Name
FlyBase ID
FBal0221218
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the P{EPgy2}EY10782 insertion, resulting in a 783bp deletion that removes the first two exons of the elgi transcription unit.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

elgi1/elgi1, elgi1/elgi2 and elgi1/Df(3L)BSC575 (but not elgi1/+) flies exhibit a significant increase in size of the wing and a significantly reduced spacing between the anterior and posterior cross veins when compared to control adults.

elgi1 homozygotes exhibit significantly larger wing discs when compared to control third instar larvae.

elgi1/elgi1 and elgi1/Df(3L)BSC575 flies do not exhibit any defect in wing hair polarity when compared to control adults.

Mutant females have normal ovarian morphology and are fertile, but progression from prophase I to metaphase I occurs prematurely in the mutant oocytes. Nuclear envelope breakdown in the mutant oocytes also occurs prematurely.

Stage 14 mutant oocytes are dehydrated, as occurs in wild-type oocytes at this stage.

elgi1/elgi2 oocytes undergo a premature metaphase I.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (2)