Allele Dmel\Manf^Scer\UAS.cPa

General Information
Symbol	Dmel\Manf^Scer\UAS.cPa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Palgi	FlyBase ID	FBal0221495
Feature type	allele	Associated gene	Dmel\Manf

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Palgi et al., 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of a Manf cDNA. (Palgi et al., 2009)
Carried in construct	P{UAS-Manf.P} (Palgi et al., 2009)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Manf^Scer\UAS.cPa/Scer\GAL4^69B rescues Manf^Δ96 (Palgi et al., 2009) Scer\GAL4^da.G32/Manf^Scer\UAS.cPa rescues Manf^Δ96 (Palgi et al., 2009) Scer\GAL4^tub.PU/Manf^Scer\UAS.cPa rescues Manf^Δ96 (Palgi et al., 2009)
Fails to rescue	Manf^Scer\UAS.cPa/Scer\GAL4^c135 fails to rescue Manf^Δ96 (Palgi et al., 2009)
Comments	Expression of Manf[Scer\UAS.cPa] under the control of one of Scer\GAL4[da.G32], Scer\GAL4[tub] or Scer\GAL4[69B] rescues the larval lethality of Manf[Δ96] animals (assayed by survival into the pupal stage). Expression of Manf[Scer\UAS.cPa] under the control of Scer\GAL4[69B] rescues the embryonic lethality of Manf[Δ96] embryos that lack both maternal and zygotic Manf[+] function. (Palgi et al., 2009)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Manf^Scer\UAS.cPa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Palgi
Secondary FlyBase IDs

References ( 1 )
Research paper	Palgi et al., 2009, Proc. Natl. Acad. Sci. U.S.A. 106(7): 2429--2434 Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. [FBrf0206690]

Allele Dmel\ManfScer\UAS.cPa

Allele Dmel\Manf^Scer\UAS.cPa