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General Information
Symbol
Dmel\dppUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0221546
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dpp
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of dpp.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Forced expression of dppScer\UAS.cUa driven by Scer\GAL4ey.PU appears to initiate ectopic eye formation at the anterior margin of the eye field. Often the result is the production of two compound eyes being generated from a single retinal field.
63-day old germaria expressing dppScer\UAS.cUa via Scer\GAL4hh.PU (with expression controlled via 'UAS-gal80[ts]' and temperature) have significantly fewer germline cell stems and cap cells compared to controls.
Females in which expression of dppScer\UAS.cUa under the control of Scer\GAL4bab1-Gal4 has been restricted to the adult stage using Scer\GAL80ts.αTub84B (animals are shifted to the restrictive temperature of 31[o]C when adult) show a strong germline stem cell tumour phenotype in the ovary after 3 days of dppScer\UAS.cUa expression.
Expression of dppScer\UAS.cUa under the control of Scer\GAL4nos.PG results in ectopic germline stem cells in the testis.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Expression of dppScer\UAS.cUa under the control of Scer\GAL4nos.PG significantly slows down the loss of germ cell phenotype that is seen in Stat92EF/Stat92Ej6C8 testes at 29[o]C. After 4 days at 29[o]C, 41% of the double mutant testes contain one or more germline stem cells and all of the testes retain spermatogonia. After 7 days at 29[o]C, 17% of the double mutant testes have one or more germline stem cells and 88% retain spermatogonia. Co-expression of BHDdsRNA.Sym.Scer\UAS significantly suppresses the male germline stem cell expansion phenotype caused by expression of dppScer\UAS.cUa under the control of Scer\GAL4nos.PG.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
dppScer\UAS.cUa
dppUAS.cUa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Unknown
Secondary FlyBase IDs
    References (14)