Allele Dmel\Xrp1^Exel6181

General Information
Symbol	Dmel\Xrp1^Exel6181	Species	D. melanogaster
Name		FlyBase ID	FBal0221558
Feature type	allele	Associated gene	Dmel\Xrp1

Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{XP}d06938 (Akdemir et al., 2007)
Nature of the lesion	Statement Reference Deletion breakpoint within intron 3. The deletion extends proximally from the progenitor P{XP}d06938 insertion site in intron 3, removing Xrp1 sequences upstream of the insertion site. (Akdemir et al., 2007)
Caused by aberration	Df(3R)Exel6181 (Akdemir et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class
	fertile (with Xrp1^Exel6182) (Akdemir et al., 2007) viable (with Xrp1^Exel6182) (Akdemir et al., 2007)
Phenotype Manifest In

Detailed Description
	Statement Reference Xrp1[Exel6181]/Xrp1[Exel6182] show significantly higher rates of loss-of-heterozygosity after irradiation compared to control animals. Mutant larval wing discs show apoptosis and cell cycle arrest after irradiation, as occurs in wild-type discs. (Akdemir et al., 2007)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Xrp1^Exel6181
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Akdemir et al., 2007, Oncogene 26(36): 5184--5193 p53 directs focused genomic responses in Drosophila. [FBrf0202061]

Allele Dmel\Xrp1Exel6181

Allele Dmel\Xrp1^Exel6181