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General Information
Symbol
Dmel\Taf3UAS.cPa
Species
D. melanogaster
Name
FlyBase ID
FBal0221664
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Bip2
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of bip2 coding sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The penetrance of the eye-to-wing transformation found in Scer\GAL4ey.PH; AntpScer\UAS.cBa mutants is increased upon ectopic co-expression of bip2Scer\UAS.cPa from 8% to 24%.

Ectopic expression of bip2Scer\UAS.cPa in combination with AntpScer\UAS.cBa and Nact.sev, under the control of Scer\GAL4ey.PH strongly enhances the penetrance of eye-to-wing transformation. About 80% of these flies show eye-to-wing transformation compared with 40% without co-expression of bip2Scer\UAS.cPa.

Ectopic expression of bip2Scer\UAS.cPa in combination with AntpScer\UAS.cBa and Nact.sev, under the control of Scer\GAL4ey.PH reduces the fraction of flies that show antenna-to-leg transformation from 28% to 13%.

Ectopic expression of bip2Scer\UAS.cPa in combination with AntpAAAA.Scer\UAS and Nact.sev, under the control of Scer\GAL4ey.PH appears to not affect eye-to-wing nor antenna-to-leg transformation, indicating a requirement of the YPWM motif for the Antp/bip2 interaction.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Taf3UAS.cPa
bip2Scer\UAS.cPa
bip2UAS.cPa
Name Synonyms
Secondary FlyBase IDs
    References (3)