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General Information
Symbol
Dmel\Sln6.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0230257
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of Sln wild-type sequences tagged with Tag:MYC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Sln6.Scer\UAS.T:Hsap\MYC-expressing wing discs (through Scer\GAL4Bx-MS1096) transport much higher amounts of butyrate and lactate than control discs.

Expression of Sln6.Scer\UAS.T:Hsap\MYC in the apical side of the wing disc, through Scer\GAL4e22c causes massive apoptosis when the wing disc is incubated with butyrate. However, incubation with lactate does not induce significant cell death compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Scer\GAL4e22c Sln6.Scer\UAS.T:Hsap\MYC-mediated apoptosis upon butyrate treatment is considerably suppressed in a lkb1X5 mutant background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Sln6.Scer\UAS.T:Hsap\MYC
Sln6.UAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (1)