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General Information
Symbol
Dmel\MpES.UAS.Tag:SS(wg)
Species
D. melanogaster
Name
FlyBase ID
FBal0230296
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-ES
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the endostatin domain of Mp. Tag:SS(wg) has been inserted at the N-terminal end of the Mp sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

A high proportion of embryos expressing mpES.Scer\UAS.T:wg under the control of Scer\GAL4how-24B show a generally defective body morphology. Some of the embryos do not have a recognisable nervous system, while other have a recognisable but disordered nervous system. Of those embryos that have a more normal morphology, pathfinding defects are seen in the ISNb (14.6%) and the ISN (11.5%).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The ISNb axon guidance defects seen in mpΔC12-25 embryos are rescued to wild type by expression of mpES.Scer\UAS.T:wg under the control of Scer\GAL4how-24B.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
MpES.Scer\UAS.T:SS-wg
MpES.UAS.Tag:SS(wg)
mpES.Scer\UAS.T:SS-wg
mpES.Scer\UAS.T:wg
Name Synonyms
Secondary FlyBase IDs
    References (3)