FB2025_01 , released February 20, 2025
Allele: Dmel\PpcsUbi.Tag:FLAG
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General Information
Symbol
Dmel\PpcsUbi.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0230487
Feature type
allele
Associated gene
Dmel\Ppcs
Associated Insertion(s)
Carried in Construct
P{Ubi-Ppcs.FLAG}
Also Known As
PdPPCS
Key Links
Transgenic product class
wild_type
(Bosveld et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bosveld et al., 2008)
Mutagen
in vitro construct
(Bosveld et al., 2008)
Progenitor genotype
Carried in construct
P{Ubi-Ppcs.FLAG}
Cytology
Description

A ubiquitin promoter drives expression of Ppcs which is tagged at the N-terminal end with Tag:FLAG.

(Bosveld et al., 2008)
Allele components
Component
Use(s)
Encoded product / tool
Ppcs
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      PpcsUbi.Tag:FLAG rescues Ppcs1

      (Bosveld et al., 2008)
      Partially rescues

      PpcsUbi.Tag:FLAG partially rescues Ppcs1

      (Bosveld et al., 2008)

      PpcsUbi.Tag:FLAG partially rescues Ppcs1

      (Bosveld et al., 2008)
      Comments

      The abnormal chromatin morphology seen in the nurse cells of Ppcs1 homozygous stage 6-8 egg chambers is rescued by PpcsUbi.T:Zzzz\FLAG, although 11.1% of the rescued egg chambers have more than 15 nurse cell nuclei.

      PpcsUbi.T:Zzzz\FLAG suppresses the ectopic wing vein and ectopic scutellar bristle phenotype of Ppcs1 homozygotes.

      (Bosveld et al., 2008)

      PpcsUbi.T:Zzzz\FLAG rescues the impaired locomotor phenotype, decreased lifespan, sensitivity to irradiation and decreased levels of triglycerides of Ppcs1 homozygotes.

      (Bosveld et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      PpcsUbi.T:Zzzz\FLAG
      PpcsUbi.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (3)