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General Information
Symbol
Dmel\Rbsn-5C241
Species
D. melanogaster
Name
FlyBase ID
FBal0230493
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T8161093A

Amino acid change:

L315term | Rbsn-5-PA

Reported amino acid change:

?315term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: ?315term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Oocytes in homozygous female germline clones do not incorporate either auto-fluorescent granules derived from endocytosed yolk proteins or the FM4-64 dye (a marker for endocytosis), in contrast to wild-type oocytes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

Rbsn-5C241/Rbsn-5C241 is an enhancer of filamentous actin & oocyte phenotype of Scer\GAL4VP16.mat.αTub67C, oskbcd.3'UTR.UASp

Additional Comments
Genetic Interactions
Statement
Reference

The fraction of oocytes showing endocytic activity in EndoB54/Rbsn-5C241 double heterozygotes is not reduced compared to either single heterozygote.

Oocytes of homozygous Rbsn-5C241 female germline clones which are also expressing oskbcd.3'UTR.Scer\UAS.P\T under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 show large aberrant F-actin aggregates at the anterior region of the oocyte.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)