FlyBase Allele Report: Dmel\Hsc70-5[KK100233]

Third instar larvae expressing Hsc70-5^KK100233 under the control of Scer\GAL4^elav.PU are sluggish: their crawling velocity is reduced and the righting reflex delayed. Their neuromuscular junction exhibits defects: mitochondria are decreased in content (fewer, smaller and rounder mitochondria), increased proportion of postsynaptic densities unopposed by active zones, and microtubule defects (fewer microtubule loops in terminal boutons and fewer boutons connected to a stable microtubule network); there are more frequent spontaneous excitatory junctional potentials but with decreased amplitude and decreased quantal content, decreased evoked excitatory junctional potentials, and progressive increase in evoked excitatory junctional potential failure upon 10Hz stimulation.

Induced expression of Hsc70-5^KK100233 under the combined control of Scer\GAL4^elav.PU from 5d after egg laying allows individuals reaching adulthood. Adults exhibit decreased climbing ability and abnormal wing posture, and are short lived.

(Zhu et al., 2021)

The expression of Hsc70-5^KK100233 under the control of Scer\GAL4^c564 leads to lethality.

(Kumar et al., 2016)

Expression via Scer\GAL4^tub.PU results in fragmented mitochondria and decreased mitochondrial membrane potential in peripodial cells of wing discs.

Expression via Scer\GAL4^tub.PU results in increased mitophagy in peripodial cells of wing discs.

Expression via Scer\GAL4^esg-NP5130 results in increased cell death of adult midgut progenitors.

(Banerjee and Chinthapalli, 2014)

Expression of Hsc70-5^KK100233 under the control of Scer\GAL4^GMR.PF does not cause any changes in external eye morphology upon fly ageing.

Knockdown of Hsc70-5 through expression of Hsc70-5^KK100233 in DA neurons using Scer\GAL4^Ddc.PL or Scer\GAL4^ple.PF, but not in sensory neurons, results in lethality during the larval or pupal stages.

Knockdown of Hsc70-5 through expression of Hsc70-5^KK100233 in motoneurons using Scer\GAL4^RapGAP1-OK6, Scer\GAL4^VGlut-OK371, or Scer\GAL4^D42, results in either larval or pupal lethality.

Expression of Hsc70-5^KK100233 in the developing eye, under the control of Scer\GAL4^GMR.PF does not cause degeneration in the external eyes of adult flies.

Pan-neuronal expression of Hsc70-5^KK100233 under the control of Scer\GAL4^elav-C155, at 18[o]C, results in death before eclosion to adulthood. Larvae display no abnormal body-posture at rest or during locomotion.

Suppression of early lethality in flies expressing Hsc70-5^KK100233 under the control of Scer\GAL4^elav-C155, through co-expression of Scer\GAL80^ts.αTub84B, results in locomotion and body posture defects. These flies exhibit a 50% decrease in cellular ATP levels.

(Zhu et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, enhanceable by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by tko^HMS01695, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by tko^HMS01695, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Sytβ^JF02593, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Sytβ^JF02593, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Snap25^JF02615, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Snap25^JF02615, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Syx7^JF02436, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Syx7^JF02436, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by EndoA^JF02758, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by EndoA^JF02758, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Sec15^JF02649, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Sec15^JF02649, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by brp^RNAi.UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by brp^RNAi.UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Eps-15^JF03257, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Eps-15^JF03257, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Rop^HM05140, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Rop^HM05140, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by Rph^JF01970, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has short lived phenotype, enhanceable by Pink1^UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by Rph^JF01970, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, enhanceable by VGlut1^JF02689, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, enhanceable by VGlut1^JF02689, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, enhanceable by Pink1^UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, enhanceable by Pink1^UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has short lived phenotype, enhanceable by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

NOT Enhanced by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, non-enhanceable by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Suppressed by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has lethal - all die before end of pupal stage phenotype, suppressible by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible | partially by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible | partially by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Atg101^HMS01349, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Atg12^JF02704, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Atg5^JF02703, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Vps15^GL00085, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Atg7^JF02787, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Atg8a^HMS01328, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Buffy^RNAi.UAS, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Atg101^HMS01349, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Atg12^JF02704, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Atg5^JF02703, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Atg7^JF02787, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Atg8a^HMS01328, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Vps15^GL00085, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Buffy^RNAi.UAS, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by DCTN1-p150^JF02803, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by DCTN2-p50^HM05084, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by dj-1β^JF01202, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, suppressible by Lrrk^HMS00456, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by DCTN1-p150^JF02803, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by dj-1β^JF01202, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by Lrrk^HMS00456, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, suppressible by DCTN2-p50^HM05084, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Atg12^JF02704, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Atg7^JF02787, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Atg5^JF02703, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Atg101^HMS01349, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible by Atg101^HMS01349, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible by Atg12^JF02704, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible by Atg7^JF02787, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, suppressible by Atg5^JF02703, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible by Atg101^HMS01349, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible by Atg5^JF02703, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible by Atg12^JF02704, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible by Atg7^JF02787, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, suppressible | partially by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, suppressible | partially by Pink1^UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^NP5130 has increased cell death phenotype, suppressible by dor[+]/dor⁴

(Banerjee and Chinthapalli, 2014)

Hsc70-5^KK100233, Scer\GAL4^NP5130 has increased cell death phenotype, suppressible by Opa1^UAS.Tag:FLAG, Scer\GAL4^NP5130

(Banerjee and Chinthapalli, 2014)

Hsc70-5^KK100233, Scer\GAL4^NP5130 has increased cell death phenotype, suppressible by Drp1^GD10456, Scer\GAL4^NP5130

(Banerjee and Chinthapalli, 2014)

NOT suppressed by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has lethal - all die before end of pupal stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has lethal - all die before end of pupal stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has lethal - all die before end of pupal stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | adult stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has visible | adult stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal heat stress response | adult stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has paralytic | adult stage | heat sensitive phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has abnormal locomotor behavior | third instar larval stage phenotype, non-suppressible by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Suppressor of

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^ey.PH is a suppressor of visible | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Even et al., 2019)

Hsc70-5^KK100233, Scer\GAL4^ey.PH is a suppressor of neoplasia | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Even et al., 2019)

Hsc70-5^KK100233, Scer\GAL4^ey.PH is a suppressor of visible | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Even et al., 2019)

Hsc70-5^KK100233, Scer\GAL4^ey.PH is a suppressor of neoplasia | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Even et al., 2019)

Phenotype Manifest In

Enhanced by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, enhanceable by Pink1^UAS.cUa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^Tub.PU has mitochondrion phenotype, enhanceable by Pka-C1^KK108966, Scer\GAL4^Tub.PU

(Banerjee and Chinthapalli, 2014)

NOT Enhanced by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-enhanceable by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has microtubule | third instar larval stage phenotype, non-enhanceable by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Suppressed by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, suppressible by Atg101^HMS01349, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, suppressible by Atg5^JF02703, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, suppressible by Atg12^JF02704, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, suppressible by Atg7^JF02787, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has mitochondrion | third instar larval stage phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has mitochondrion | third instar larval stage | decreased number phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, suppressible by Atg1^JF02273, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has mitochondrion | third instar larval stage phenotype, suppressible | partially by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, suppressible | partially by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, suppressible | partially by Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^Tub.PU has mitochondrion phenotype, suppressible by Opa1^UAS.Tag:FLAG, Scer\GAL4^Tub.PU

(Banerjee and Chinthapalli, 2014)

Hsc70-5^KK100233, Scer\GAL4^Tub.PU has mitochondrion phenotype, suppressible by Drp1^GD10456, Scer\GAL4^Tub.PU

(Banerjee and Chinthapalli, 2014)

Hsc70-5^KK100233, Scer\GAL4^NP5130 has adult midgut progenitor cell phenotype, suppressible by dor[+]/dor⁴

(Banerjee and Chinthapalli, 2014)

Hsc70-5^KK100233, Scer\GAL4^NP5130 has adult midgut progenitor cell phenotype, suppressible by Opa1^UAS.Tag:FLAG, Scer\GAL4^NP5130

(Banerjee and Chinthapalli, 2014)

Hsc70-5^KK100233, Scer\GAL4^NP5130 has adult midgut progenitor cell phenotype, suppressible by Drp1^GD10456, Scer\GAL4^NP5130

(Banerjee and Chinthapalli, 2014)

NOT suppressed by

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has microtubule | third instar larval stage phenotype, non-suppressible by Atg1^UAS.cSa, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has mitochondrion | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has mitochondrion | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has mitochondrion | third instar larval stage phenotype, non-suppressible by Hsap\HSPA9^{R126W.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, non-suppressible by Hsap\HSPA9^{A476T.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsc70-5^KK100233, Scer\GAL4^elav.PU has wing phenotype, non-suppressible by Hsap\HSPA9^{P509S.UAS.cZa}, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Suppressor of

Statement

Reference

Hsc70-5^KK100233, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Even et al., 2019)

Hsc70-5^KK100233, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH

(Even et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Hsc70-5^KK100233 is rescued by Scer\GAL4^elav.PU/Hsc70-5^UAS.cZa

(Zhu et al., 2021)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v106236

P{KK100233}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hsc70-5^KK100233

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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