During sensory organ precursor division, spindle asymmetry between pIIa and pIIb is abolished when PatroninKK100898
is knocked down.
The expression of PatroninKK100898
under the control of Scer\GAL4221
, in combination with Dicer-2 for efficient RNAi, results in third instar larval class I abdominal dorsal multidendritic ddaD and ddaE neurons exhibiting dendrite branch misrouting, as compared to controls; expression under the control of Scer\GAL4ppk.PG
, in combination with Dicer-2 for efficient RNAi, results in third instar larval class IV abdominal dorsal multidendritic ddaC neurons exhibiting reduced dendritic arborization and abnormal dendritic terminals, as compared to controls.