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General Information
Symbol
Dmel\RafKK100982
Species
D. melanogaster
Name
FlyBase ID
FBal0231022
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of RafKK100982 under the control of Scer\GAL4phm.PO significantly reduces the circadian rhythmicity of adult emergence after transfer to constant darkness, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The overgrowth and increased number of progenitor cells characteristic for cnoR2;scrib1 clones is not significantly suppressed by Scer\GAL4Dll-md23-driven expression of RafKK100982 in the mutant clones.

Xenogenetic Interactions
Statement
Reference

Expression of phlKK100982 partially suppresses the external eye phenotype and photoreceptor degeneration seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF. The progressive impairment of motor performance and reduction in lifespan seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4nrv2.PS are also partially rescued.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
RafKK100982
phlKK100982
Name Synonyms
Secondary FlyBase IDs
    References (4)